Parosteal extra-axial chordoma of the second metacarpal bone: a case report with literature review
- 50 Downloads
Extra-axial chordoma is a chordoma that occurs in non-axial locations. It is a very rare tumor, with 20 cases reported to date; 14 in bone and six in soft tissue. Of the 14 skeletal extra-axial chordomas, ten were intramedullary and four were intracortical. We report the first case of parosteal extra-axial chordoma arising in the second metacarpal bone, expressing brachyury on immunohistochemical analysis, and describe the pathologic and radiologic findings. We suggest that extra-axial chordoma can occur in parosteal bone lesions or the hand, without features of bone distribution or bone-specific sites.
KeywordsChordoma Parachordoma Extra-axial chordoma Brachyury Metacarpal bone Parosteal
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflicts of interest.
All authors had access to data and a role in writing the manuscript.
- 1.Fletcher CDM, Bridge JA, Hogendoorn P, Mertens F. WHO Classification of Tumours of Soft Tissue and Bone. Lyon: IARC; 2013.Google Scholar
- 23.Athanasian EA. Bone and soft tissue tumors. In: Hotchkiss RN, Pederson WC, Wolfe SH, Kozen SH, editors. Green’s operative hand surgery. 6th ed. Philadelphia: Elsevier Health; 2010.Google Scholar