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Periosteal mesenchymal chondrosarcoma of the tibia with multifocal bone metastases: a case report

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A Letter to the editor to this article was published on 03 February 2018

An Erratum to this article was published on 08 April 2017

This article has been updated

Abstract

Mesenchymal chondrosarcoma of bone is a rare high-grade variant of chondrosarcoma, which typically has central intramedullary location. The tumor is characterized by admixture of highly anaplastic small round malignant cells and islands of mineralized low-grade hyaline cartilage. It is most unusual for this tumor to arise on the surface of a long bone. We describe a patient with periosteal mesenchymal chondrosarcoma that arose at the surface of the right tibia with multifocal bone metastases. Radiographic, CT, MRI, and PET-CT features of this unusual tumor are presented.

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  • 08 April 2017

    An erratum to this article has been published.

References

  1. Nugent D, Gheong D, Monforte H, Ayala AG, Letson D, et al. Periosteal mesenchymal chondrosarcoma in the distal part of the tibia of a four-year-old boy. A case report. JBJS Case Connect. 2013;3:e117.

    Article  PubMed  Google Scholar 

  2. Hoang MP, Suarez PA, Donner LR, Ro JY, et al. Mesenchymal chondrosarcoma: a small cell neoplasm with polyphenotypic differentiation. Int J Surg Pathol. 2000;8:291–301.

    Article  PubMed  Google Scholar 

  3. Dantonello TM, Int-Veen C, Leuschner I, Schuck A, et al. Mesenchymal chondrosarcoma of soft tissues and bone in children, adolescents and young adults. Cancer. 2008;112:2424–31.

    Article  PubMed  Google Scholar 

  4. Salvador AH, Beabout JW, Dahlin DC. Mesenchymal chondrosarcoma—observations on 30 new cases. Cancer. 1971;28:605–15.

    Article  CAS  PubMed  Google Scholar 

  5. Nakashima Y, Unni KK, Shives TC, Swee RG, Dahlin DC. Mesenchymal chondrosarcoma of bone and soft tissues. A review of 111 cases. Cancer. 1986;57:2444–53.

    Article  CAS  PubMed  Google Scholar 

  6. Bertoni F, Picci P, Bacchini P, Capanna R, et al. Mesenchymal chondrosarcoma of bone and soft tissues. Cancer. 1983;52:533–41.

    Article  CAS  PubMed  Google Scholar 

  7. Gelderblom H, Hogendoorn PCW, Dijkstra SD, van Rijswijk CS, et al. The clinical approach towards chondrosarcoma. Oncologist. 2008;13:320–9.

    Article  PubMed  Google Scholar 

  8. Lichtenstein L, Berstein D. Unusual benign and malignant chondroid tumors of bone. Cancer. 1959;12:1142–57.

    Article  Google Scholar 

  9. Huvos AG, Rosen G, Dabska M, Marcove RC. Mesenchymal chondrosarcoma. A clinicopathologic analysis of 35 patients with emphasis on treatment. Cancer. 1983;51:1230–7.

    Article  CAS  PubMed  Google Scholar 

  10. Cesari M, Bertoni F, Bacchini P, Mercuri M, Palmerini E, Ferrari S. Mesenchymal chondrosarcoma. An analysis of patients treated at a single institution. Tumori. 2007;93:423–7.

    PubMed  Google Scholar 

  11. Littrell LA, Wenger DE, Wold LE, et al. Radiographic, CT and MRI features of dedifferentiated chondrosarcoma: a retrospective review of 174 de novo cases. RadioGraphics. 2004;24:1397–409.

    Article  PubMed  Google Scholar 

  12. Feldmam F, Heertum RV, Saxena C, Parisien M. 18FDG-PET applications for cartilage neoplasms. Skeletal Radiol. 2005;34:367–74.

    Article  Google Scholar 

  13. Harwood AR, Ivan JK, Fornasier VL. Mesenchymal chondrosarcoma: a report of 17 cases. Clin Orthop Rel Res. 1981;158:144–8.

    Google Scholar 

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Authors and Affiliations

  1. Department of Diagnostic Imaging, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA

    Rajendra Kumar, Cihan Duran & Behrang Amini

  2. Department of Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA

    Dejka M. Araujo

  3. Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Unit 1475, 1515 Holcombe Blvd, Unit 1475, Houston, Texas, 77030, USA

    Wi-Lei Wang

Authors
  1. Rajendra Kumar
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  2. Cihan Duran
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  3. Behrang Amini
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  4. Dejka M. Araujo
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  5. Wi-Lei Wang
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Corresponding author

Correspondence to Rajendra Kumar.

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The authors declare that they have no conflicts of interest.

Informed consent

Informed consent for this case report was obtained from the legal party responsible for the participant included in this case report as per the Institutional Review Board rules.

Additional information

An erratum to this article is available at https://doi.org/10.1007/s00256-017-2653-2.

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Kumar, R., Duran, C., Amini, B. et al. Periosteal mesenchymal chondrosarcoma of the tibia with multifocal bone metastases: a case report. Skeletal Radiol 46, 995–1000 (2017). https://doi.org/10.1007/s00256-017-2626-5

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  • DOI: https://doi.org/10.1007/s00256-017-2626-5

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