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Percutaneous treatment of insufficiency fractures

Principles, technique and review of literature

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Abstract

Insufficiency fractures of the pelvis, sacrum, spine, and long bones are painful, debilitating, and are common consequences of osteoporosis. Conventional treatment for these fractures varies from conservative therapy to surgery with plate and screw fixation. The former fails to address the underlying problem of fracture and frequently does not alleviate symptoms, while the latter is invasive and not always possible in older populations with low bone density and numerous co-morbidities. Osseous augmentation with polymethylmethacrylate (PMMA) has been used for over two decades to treat fractures related to osteoporosis, but has not been commonly used to treat fractures outside of the vertebral bodies. Osseous augmentation with PMMA is an image-guided procedure and various techniques have been utilized to treat fracture in different locations. We describe various techniques for image-guided osseous augmentation and treatment of insufficiency fractures with bothPMMA and allograft bone for fractures of the pelvis including sacrum, acetabulum, pubic symphysis, pubic rami ilium; appendicular skeleton including distal radius, proximal femur, and vertebral body. We also describe the potential risks and complications associated with percutaneous treatment of insufficiency fractures and techniques to avoid the pitfalls of the various procedures. We will present the process for patient follow-up and data regarding the pre- and postprocedure pain response in patients undergoing treatment for pelvic insufficiency fractures.

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References

  1. Melton LJ III. Epidemiology of spinal osteoporosis. Spine. 1997;15(22):2S–11S.

    Article  Google Scholar 

  2. Evans AJ, Jensen ME, Kip KE, et al. Vertebral compression fractures: pain reduction and improvement in functional mobility after percutaneous polymethylmethacrylate vertebroplasty-retrospective report of 245 cases. Radiology. 2003;226:366–72.

    Article  Google Scholar 

  3. Harrington KD, Sim FH, Enis JE, Johnston JO, Diok HM, Gristina AG. Methylmethacrylate as an adjunct in internal fixation of pathological fractures. Experience with three hundred and seventy-five cases. J Bone Joint Surg Am. 1976;58:1047–55.

    Article  CAS  Google Scholar 

  4. Hulme PA, Krebs J, Ferguson SJ, Berlemann U. Vertebroplasty and kyphoplasty: a systematic review of 69 clinical studies. Spine. 2006;31:1983–2001.

    Article  Google Scholar 

  5. Layton KF, Thielen KR, Wald JT. Percutaneous sacroplasty using CT fluoroscopy. AJNR Am J Neuroradiol. 2006;27:356–8.

    CAS  PubMed  Google Scholar 

  6. Galibert P, Deramond H, Rosat P, Le Gars D. Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty. Neurochirurgie. 1987;33:166–8.

    CAS  Google Scholar 

  7. Wilson DR, Myers ER, Mathis JM, et al. Effect of augmentation on the mechanics of vertebral wedge fractures. Spine. 2000;25:158–165.

    Article  CAS  Google Scholar 

  8. Belkoff SM, Mathis JM, Fenton DC, Scribner RM, Reiley ME, Talmadge K. An ex vivo biomechanical evaluation of an inflatable bone tamp used in the treatment of compression fracture. Spine. 2001;26:151–6.

    Article  CAS  Google Scholar 

  9. Mathis JM, Ortiz AO, Zoarski GH. Vertebroplasty versus kyphoplasty: a comparison and contrast. AJNR Am J Neuroradiol. 2004;25:840–5.

    PubMed  Google Scholar 

  10. Gangi A, Guth S, Imbert JP, Marin H, Dietemann JL. Percutaneous vertebroplasty: indications, technique, and results. Radiographics. 2003;23:e10.

    Article  Google Scholar 

  11. Brown DB, Gilula LA, Sehgal M, Shimony JS. Treatment of chronic symptomatic vertebral compression fractures with percutaneous vertebroplasty. AJR Am J Roentgenol. 2004;182:319–22.

    Article  Google Scholar 

  12. Kaufmann TJ, Jensen ME, Schweickert PA, Marx WF, Kallmes DF. Age of fracture and clinical outcomes of percutaneous vertebroplasty. AJNR Am J Neuroradiol. 2001;22:1860–3.

    CAS  PubMed  Google Scholar 

  13. Peh WC, Gilula LA, Peck D. Percutaneous vertebroplasty for severe osteoporotic vertebral body compression fractures. Radiology. 2002;223:121–6.

    Article  Google Scholar 

  14. Appel NB, Gilula LA. Percutaneous vertebroplasty in patient with spinal canal compromise. AJR Am J Roentgenol. 2004;182:947–51.

    Article  Google Scholar 

  15. Shimony JS, Gilula LA, Zeller AJ, Brown DB. Percutaneous vertebroplasty for malignant compression fractures with epidural involvement. Radiology. 2004;232:846–53.

    Article  Google Scholar 

  16. Mathis JM, Barr JD, Belkoff SM, Barr MS, Jensen ME, Deramond H. Percutaneous vertebroplasty: a developing standard of care for vertebral compression fractures. AJNR Am J Neuroradiol. 2001;22:373–81.

    CAS  PubMed  Google Scholar 

  17. Beall DP, Braswell JJ, Martin HD, Stapp AM, Puckett TA, Stechison MT. Technical strategies and anatomic considerations for parapedicular access to thoracic and lumbar vertebral bodies. Skeletal Radiol. 2007;36:47–52.

    Article  Google Scholar 

  18. Amar AP, Larsen DW, Esnaashari NP, Albuquerque FC, Lavine SD, Teitelbaum GP. Percutaneous transpedicular polymethylmethacrylate vertebroplasty for the treatment of spinal compression fractures. Neurosurgery. 2001;49:1105–15.

    CAS  PubMed  Google Scholar 

  19. Kim AK, Jensen ME, Dion JE, Schweickert PA, Kaufmann TJ, Kallmes DF. Unilateral transpedicular percutaneous vertebroplasty: initial experience. Radiology. 2002;222:737–41.

    Article  Google Scholar 

  20. Peh WC, Munk PL, Rashid F, Gilula LA. Percutaneous vertebral augmentation: vertebroplasty, kyphoplasty and skyphoplasty. Radiol Clin North Am. 2008;46:611–35.

    Article  Google Scholar 

  21. Beall DP, Stanfield M, Martin HD, Stapp AM. Transoral vertebral augmentation with polymethylmethacrylate in the treatment of a patient with a dens fracture nonunion and subarticular vertebral body fracture of C2. Skeletal Radiol. 2007;36:453–8.

    Article  Google Scholar 

  22. Kallmes DF, Jensen ME. Percutaneous vertebroplasty. Radiology. 2003;229:27–36.

    Article  Google Scholar 

  23. Cotten A, Boutry N, Cortet B, et al. Percutaneous vertebroplasty: state of the art. Radiographics. 1998;18:311–20.

    Article  CAS  Google Scholar 

  24. Deramond H, Depriester C, Galibert P, Le Gars D. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results. Radiol Clin North Am. 1998;36:433–46.

    Article  Google Scholar 

  25. Jacofsky DJ, Papagelopoulos PJ, Sim FH. Advances and challenges in the surgical treatment of metastatic bone disease. Clin Orthop Relat Res. 2003;415S:14–8.

    Article  Google Scholar 

  26. Belkoff SM, Mathis JM, Jasper LE, et al. The biomechanics of vertebroplasty: the effect of cement volume on mechanical behavior. Spine. 2001;26:1537–41.

    Article  CAS  Google Scholar 

  27. Barr JD, Barr MS, Lemley TJ, McCann RM. Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine. 2000;25:923–8.

    Article  CAS  Google Scholar 

  28. Berlemann U, Ferguson SJ, Nolte LP, Heini PF. Adjacent vertebral failure after vertebroplasty. A biomechanical investigation. J Bone Joint Surg Br. 2002;84:748–52.

    Article  CAS  Google Scholar 

  29. Heini PF, Wälchli B, Berlemann U. Percutaneous transpedicular vertebroplasty with PMMA: operative technique and early results. A perspective study for the treatment of osteoporotic compression fractures. Eur Spine J. 2000;9:445–50.

    Article  CAS  Google Scholar 

  30. Dean JR, Ison KT, Gishen P. The strengthening effect of percutaneous vertebroplasty. Clin Radiol. 2000;55:471–6.

    Article  CAS  Google Scholar 

  31. Tohmeh AG, Mathis JM, Fenton DC, Levine AM, Belkoff SM. Biomechanical efficacy of unipedicular versus bipedicular vertebroplasty for the management of osteoporotic compression fractures. Spine. 1999;24:1772–6.

    Article  CAS  Google Scholar 

  32. Mathis JM. Procedural techniques and material: tumors and osteoporotic fractures. In: John M, Mathis JM, Hervé Deramond, Stephan M, editors. Percutaneous vertebroplasty. New York: Springer; 2002. p. 81–107.

    Chapter  Google Scholar 

  33. Lam S, Khoo LT. A novel percutaneous system for bone graft delivery and containment for elevation and stabilization of vertebral compression fractures—technical note. Neurosurg Focus. 2005;18:e10.

    Article  Google Scholar 

  34. Chiu JC, Stechison MT. Percutaneous vertebral augmentation and reconstruction with an intravertebral mesh and morcelized bone graft. Surg Technol Int. 2005;14:287–96.

    PubMed  Google Scholar 

  35. Frey ME, DePalma MJ, Cifu DX, Bhagia SM, Daitch JS. Efficacy and safety of percutaneous sacroplasty for painful osteoporotic sacral insufficiency fractures: a prospective, multicenter trial. Spine. 2007;32:1635–40.

    Article  Google Scholar 

  36. Babayev M, Lachmann E, Nagler W. The controversy surrounding sacral insufficiency fractures: to ambulate or not to ambulate? Am J Phys Med Rehabil. 2000;79:404–9.

    Article  CAS  Google Scholar 

  37. Pommersheim W, Huang-Hellinger F, Baker M, Morris P. Sacroplasty: a treatment for sacral insufficiency fractures. AJNR Am J Neuroradiol. 2003;24:1003–7.

    PubMed  Google Scholar 

  38. Taillandier J, Langue F, Alemanni M, Taillandier-Heriche E. Mortality and functional outcomes of pelvic insufficiency fractures in older patients. Joint Bone Spine. 2003;70:287–9.

    Article  Google Scholar 

  39. Beall DP, D’Souza SL, Costello RF, et al. Percutaneous augmentation of the superior pubic ramus with polymethyl methacrylate: treatment of acute traumatic and chronic insufficiency fractures. Skeletal Radiol. 2007;36:979–83.

    Article  Google Scholar 

  40. Garant M. Sacroplasty: a new treatment for sacral insufficiency fracture. J Vasc Interv Radiol. 2002;13:1265–7.

    Article  Google Scholar 

  41. Heron J, Connell DA, James SL. CT-guided sacroplasty for the treatment of sacral insufficiency fractures. Clin Radiol. 2007;62:1094–100.

    Article  CAS  Google Scholar 

  42. Deen HG, Nottmeier EW. Balloon kyphoplasty for treatment of sacral insufficiency fractures. Report of three cases. Neurosurg Focus. 2005;18:e7.

    PubMed  Google Scholar 

  43. Carrino JA, Blanco R. Magnetic resonance-guided musculoskeletal interventional radiology. Semin Musculoskelet Radiol. 2006;10:159–74.

    Article  Google Scholar 

  44. Butler CL, Given CA II, Michel SJ, Tibbs PA. Percutaneous sacroplasty for the treatment of sacral insufficiency fractures. AJR Am J Roentgenol. 2005;184:1956–9.

    Article  Google Scholar 

  45. Cassidy C, Jupiter JB, Cohen M, et al. Norian SRS cement compared with conventional fixation in distal radial fractures. A randomized study. J Bone Joint Surg Am. 2003;85:2127–37.

    Article  Google Scholar 

  46. Schmalholz A. External skeletal fixation versus cement fixation in the treatment of redislocated Colles’ fracture. Clin Orthop Relat Res. 1990;254:236–41.

    Google Scholar 

  47. Schmalholz A. Bone cement for redislocated Colles’ fracture. A prospective comparison with closed treatment. Acta Orthop Scand. 1989;60:212–7.

    Article  CAS  Google Scholar 

  48. Choe DH, Marom EM, Ahrar K, Truong MT, Madewell JE. Pulmonary embolism of polymethylmethacrylate during percutaneous vertebroplasty and kyphoplasty. AJR Am J Roentgenol. 2004;183:1097–102.

    Article  Google Scholar 

  49. Hodler J, Peck D, Gilula LA. Midterm outcome after vertebroplasty: predictive value of technical and patient-related factors. Radiology. 2003;227:662–8.

    Article  Google Scholar 

  50. Francois K, Taeymans Y, Poffyn B, Van Nooten G. Successful management of a large pulmonary cement embolus after percutaneous vertebroplasty: a case report. Spine. 2003;28:424–5.

    Article  Google Scholar 

  51. Frankel BM, Monroe T, Wang C. Percutaneous vertebral augmentation: an elevation in adjacent-level fracture risk in kyphoplasty as compared with vertebroplasty. Spine J. 2007;7:575–82.

    Article  Google Scholar 

  52. Lindsay R, Silverman SL, Cooper C, et al. Risk of new vertebral fracture in the year following a fracture. JAMA. 2001;285:320–3.

    Article  CAS  Google Scholar 

  53. Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. AJNR Am J Neuroradiol. 1997;18:1897–904.

    CAS  PubMed  Google Scholar 

  54. Kirby BS, Doyle A, Gilula LA. Acute bronchospasm due to exposure to polymethylmethacrylate vapors during percutaneous vertebroplasty. AJR Am J Roentgenol. 2003;180:543–4.

    Article  Google Scholar 

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Acknowledgement

All work originated at Edmond Medical Center, Edmond, OK, USA, and performed by the personnel of Clinical Radiology of Oklahoma.

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Correspondence to Douglas P. Beall.

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Beall, D.P., Datir, A., D’Souza, S.L. et al. Percutaneous treatment of insufficiency fractures. Skeletal Radiol 39, 117–130 (2010). https://doi.org/10.1007/s00256-009-0722-x

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  • DOI: https://doi.org/10.1007/s00256-009-0722-x

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