Fig. 1

a The plasma device consisting of the plasma driving unit (plasma pulser) and plasma pad; b plasma pad with scale in cm. Plasma pad showing the side with prefabricated holes that is in contact with the skin; c plasma is generated in the small holes; d schematic diagram of device for the treatment of samples on chicken meat as a support layer; layers of human skin (0.7 mm) were used to increase the distance between sample and plasma; e schematic diagram of device during treatment of healthy volunteers. HV, high voltage; CEM, collagen elastin matrix