Recent advances in glyphosate biodegradation
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Glyphosate has emerged as the most widespread herbicide to control annual and perennial weeds. Massive use of glyphosate for decades has resulted in its ubiquitous presence in the environment, and poses a threat to humans and ecosystem. Different approaches such as adsorption, photocatalytic degradation, and microbial degradation have been studied to break down glyphosate in the environment. Among these, microbial degradation is the most effective and eco-friendly method. During its degradation, various microorganisms can use glyphosate as a sole source of phosphorus, carbon, and nitrogen. Major glyphosate degradation pathways and its metabolites have been frequently investigated, but the related enzymes and genes have been rarely studied. There are many reviews about the toxicity and fate of glyphosate and its major metabolite, aminomethylphosphonic acid. However, there is lack of reviews on biodegradation and bioremediation of glyphosate. The aims of this review are to summarize the microbial degradation of glyphosate and discuss the potential of glyphosate-degrading microorganisms to bioremediate glyphosate-contaminated environments. This review will provide an instructive direction to apply glyphosate-degrading microorganisms in the environment for bioremediation.
KeywordsGlyphosate Biodegradation mechanism Carbon-phosphorus lyase Aminomethylphosphonic acid Bioremediation
This study was partially funded by grants from the National Natural Science Foundation of China (31401763), the National Key Project for Basic Research (2015CB150600), Guangdong Natural Science Funds for Distinguished Young Scholar (2015A030306038), the Science and Technology Planning Project of Guangdong Province (2016A020210106, 2017A010105008) and Pearl River S&T Nova Program of Guangzhou (201506010006).
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
- Duke SO, Powles SB (2008) Glyphosate: a once‐in‐a‐century herbicide. Pest Manage Sci 64(4):319–325Google Scholar
- Firdous S, Iqbal S, Anwar S (2017a) Optimization and modeling of glyphosate biodegradation by a novel Comamonas odontotermitis P2 through response surface methodology. Pedosphere. https://doi.org/10.1016/S1002-0160(17)60381-3
- Hadi F, Mousavi A, Salmanian AH, Akbari Noghabi K (2012) Glyphosate tolerance in transgenic canola by a modified glyphosate oxidoreductase (gox) gene. Prog Biol Sci 2(1):50–58Google Scholar
- Haslam E (2014) The shikimate pathway: biosynthesis of natural products series. Elsevier, New YorkGoogle Scholar
- Karigar CS, Rao SS (2011) Role of microbial enzymes in the bioremediation of pollutants: a review. Enzym Res 7:805187Google Scholar
- McAuliffe KS, Hallas LE, Kulpa CF (1990) Glyphosate degradation by Agrobacterium radiobacter isolated from activated sludge. J Ind Microbiol Biotechnol 6(3):219–221Google Scholar
- Pipke R, Amrhein N, Jacob GS, Schaefer J, Kishore GM (1987a) Metabolism of glyphosate in an Arthrobacter sp. GLP-1. FEBS J 165(2):267–273Google Scholar
- Santos-beneit F (2015) The Pho regulon: a huge regulatory network in bacteria. Front Micribiol 6:402Google Scholar
- Sharma B, Dangi AK, Shukla P (2018) Contemporary enzyme based technologies for bioremediation: a review. J Environ Manage 210:10–22Google Scholar
- Sviridov A (2012) Enzyme systems of organophosphonate catabolism of soil bacteria Achromobacter sp. and Ochrobactrum anthropi GPK3. PhD thesis (in Russian). Pushchinoa 152:120–132Google Scholar
- Sviridov AV, Shushkova TV, Zelenkova NF, Vinokurova NG, Morgunov IG, Ermakova IT, Leontievsky AA (2012) Distribution of glyphosate and methylphosphonate catabolism systems in soil bacteria Ochrobactrum anthropi and Achromobacter sp. Appl Microbiol Biotechnol 93(2):787–796CrossRefPubMedGoogle Scholar
- Sviridov A, Shushkova T, Ermakova I, Ivanova E, Leontievsky A (2014) Glyphosate: safety risks, biodegradation, and bioremediation. Current environmental issues and challenges. Springer, Dordrecht, pp 183–195Google Scholar