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Pediatric Radiology

, Volume 27, Issue 4, pp 345–347 | Cite as

A case of infantile Dubin-Johnson syndrome with high CT attenuation in the liver

  • T. Shimizu
  • T. Tawa
  • T. Maruyama
  • S. Oguchi
  • Y. Yamashiro
  • K. Yabuta

Abstract

We report a case of Dubin-Johnson syndrome (DJS) with severe infantile cholestasis and elevated computed tomography (CT) attenuation of the liver. Increased levels of urinary coproporphyrin I were found as well as pigment granules in the hepatocytes and hepatosteatosis. The CT attenuation was markedly higher in the liver of this patient at the ages of 3 and 7 months than in the spleen or kidneys. This high attenuation may be a finding specific to infantile DJS and, therefore, abdominal CT may be helpful in the diagnosis.

Keywords

Compute Tomography Attenuation Cholestasis Abdominal Compute Tomography High Attenuation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • T. Shimizu
    • 1
  • T. Tawa
    • 1
  • T. Maruyama
    • 1
  • S. Oguchi
    • 1
  • Y. Yamashiro
    • 1
  • K. Yabuta
    • 1
  1. 1.Department of Pediatrics, Juntendo University School of Medicine, 3-1-3, Hongo, Bunkyo-ku, Tokyo 113, JapanJP

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