Abstract
We report a case of Dubin-Johnson syndrome (DJS) with severe infantile cholestasis and elevated computed tomography (CT) attenuation of the liver. Increased levels of urinary coproporphyrin I were found as well as pigment granules in the hepatocytes and hepatosteatosis. The CT attenuation was markedly higher in the liver of this patient at the ages of 3 and 7 months than in the spleen or kidneys. This high attenuation may be a finding specific to infantile DJS and, therefore, abdominal CT may be helpful in the diagnosis.
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Received: 22 May 1995 Accepted: 5 March 1996
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Shimizu, T., Tawa, T., Maruyama, T. et al. A case of infantile Dubin-Johnson syndrome with high CT attenuation in the liver. Pediatric Radiology 27, 345–347 (1997). https://doi.org/10.1007/s002470050147
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DOI: https://doi.org/10.1007/s002470050147