Abstract
Objective. To determine the correlation between clinical status and 3D, fat-saturated contrast-enhanced MRI findings in assessing the response to treatment in patients with knee-joint involvement from juvenile rheumatoid arthritis (JRA). Materials and methods. Synovial hypertrophy, effusion, cartilage and epiphyseal status were scored using spin-echo (SE) T1-weighted, SE T2-weighted and contrast-enhanced, fat-suppressed 3D MRI in 42 knees of 21 patients. MRI findings were evaluated by scoring results and compared with the clinical scoring results. Progression, improvement and equivalence were analysed between 0–3 and 3–6 months, both clinically and by MRI. Results. Fat-suppression imaging generated high contrast between cartilage, synovium, effusion and bone. Correlation coefficients according to progression, improvement and equivalent findings of months 1–3 and months 3–6 comparison of clinical and MRI scores were found to be 0.50 and 0.70, respectively. Conclusion. Contrast-enhanced 3D MRI with fat suppression provides good discrimination between synovial hypertrophy and fluid. Fat-suppressed imaging offers better contrast between cartilage and synovium. Long-term MRI follow-up of JRA improves direct follow-up of pathological changes and helps in modifying treatment regimens.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 19 March 1999 Accepted: 20 March 2000
Rights and permissions
About this article
Cite this article
Cakmakci, H., Kovanlikaya, A. & Unsal, E. Short-term follow-up of the juvenile rheumatoid knee with fat-saturated 3D MRI. Pediatric Radiology 31, 189–195 (2001). https://doi.org/10.1007/s002470000371
Issue Date:
DOI: https://doi.org/10.1007/s002470000371