Pediatric Radiology

, Volume 47, Issue 12, pp 1631–1637 | Cite as

Epithelioid hemangioma of bone: radiologic and magnetic resonance imaging characteristics with histopathological correlation

  • Kathleen Schenker
  • Steven Blumer
  • Diego Jaramillo
  • Amanda L. Treece
  • Aashim Bhatia
Original Article



Epithelioid hemangioma is a rare vascular tumor that can occur in soft tissues or bone. The tumor is part of a spectrum of vascular tumors that also includes epithelioid hemangioendothelioma and angiosarcoma. When involving the bone, the tumor usually involves the metaphysis or diaphysis of the long tubular bones and most commonly occurs in adults. It has been rarely reported in pediatric patients, and in these reported patients, the tumor primarily involves the epiphysis.


To review three cases of epithelioid hemangioma of bone occurring in pediatric patients involving the epiphysis and to explore the imaging features of this tumor.

Materials and methods

Retrospectively review three cases of epithelioid hemangioma occurring in skeletally immature patients.


These tumors primarily involved the epiphyses or epiphyseal equivalent bones. One lesion was centered in the metaphysis but extended to the epiphysis. These are three cases presenting in an unusual location and at an unusual age.


Epithelioid hemangioma, though rare, can occur in pediatric patients and appears to involve the epiphyses in these patients. This is in contrast to the usual age and location reported. Epithelioid hemangioma may be considered for an epiphyseal lesion in a skeletally immature patient.


Adolescent Bone Epiphysis Epithelioid hemangioma Magnetic resonance imaging Radiography 


Compliance with ethical standards

Conflicts of interest



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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.Department of RadiologyNemours/Alfred I. duPont Hospital for ChildrenWilmingtonUSA
  2. 2.Department of RadiologyNicklaus Children’s HospitalMiamiUSA
  3. 3.Departments of Pathology and Laboratory Medicine, Children’s Hospital ColoradoUniversity of Colorado School of MedicineAuroraUSA
  4. 4.Department of RadiologyMonroe Carell Jr. Children’s Hospital at VanderbiltNashvilleUSA

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