Abstract
Background
We have clinically encountered children with fibrodysplasia ossificans progressiva who had abnormal calcaneal ossification.
Objective
To evaluate whether calcaneal ossification variants are significant radiographic findings in children with fibrodysplasia ossificans progressiva.
Materials and methods
Lateral feet radiographs in nine children who fulfilled the diagnostic criteria of fibrodysplasia ossificans progressiva were reviewed. The studies were obtained during infancy or early childhood.
Results
Fourteen lateral foot radiographs of fibrodysplasia ossificans progressiva were available for this study (ages at examination: 1-104 months). Four children ages 2 months to 11 months showed double calcaneal ossification centers; 7 children had plantar calcaneal spurs that decreased in size with age. Overall, eight of nine children with fibrodysplasia ossificans progressiva demonstrated double calcaneal ossifications and/or plantar calcaneal spurs in infancy or childhood.
Conclusion
Double calcaneal ossification centers in early infancy and plantar calcaneal spurs in childhood are frequently seen in children with fibrodysplasia ossificans progressiva and may be a useful radiologic indicator for early diagnosis.
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Acknowledgments
The authors appreciate members of skeldys.org for their enthusiastic web discussion concerning patients 2 and 3. This work was supported in partly by Research Committee on Fibrodysplasia Ossificans Progressiva from the Ministry of Health, Labor and Welfare of Japan.
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Hasegawa, S., Victoria, T., Kayserili, H. et al. Characteristic calcaneal ossification: an additional early radiographic finding in infants with fibrodysplasia ossificans progressiva. Pediatr Radiol 46, 1568–1572 (2016). https://doi.org/10.1007/s00247-016-3662-3
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DOI: https://doi.org/10.1007/s00247-016-3662-3