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Craniopharyngeal canal and its spectrum of pathology
Abele TA, Salzman KL, Harnsberger et al
AJNR (2013) Nov 1. Epub ahead of print
The craniopharyngeal canal (CPC) is a midline lucency in the sphenoid body that extends from the floor of the sella to the nasopharynx. The origin is most likely from incomplete closure of the Rathke pouch, which is a precursor of the adenohypophysis. Persistence of a visible CPC on cross-sectional imaging is uncommon beyond infancy. The authors retrospectively reviewed MR and CT imaging, and clinical data of 29 patients with craniopharyngeal canals. Age range was 1 day to 65 years, with an average age of 4 years. The authors qualitatively separated CPCs into three types: incidental canals (Type 1), canals with ectopic adenohypophysis (Type 2) and canals containing cephaloceles (Type 3A), tumors (Type 3B), or both cephaloceles and tumors (Type 3C). The range of tumors included pituitary adenoma, craniopharyngioma, dermoid, teratoma and glioma. Median...