Abstract
Background
Tracheobronchial calcifications are considered a rare radiologic finding in children. Our clinical experience indicates that this finding is not infrequently seen among children with prosthetic heart valves who have been treated with warfarin sodium.
Objective
We hypothesized that calcifications of the tracheobronchial tree are more common than previously reported in this patient population.
Materials and methods
We reviewed the medical records and imaging studies of children who underwent cardiac valve replacement at our institution to estimate the prevalence.
Results
Tracheobronchial calcifications were identified on chest radiographs in 6 out of 17 children (35%), indicating that this imaging finding might be frequently overlooked.
Conclusion
All children positive for tracheobronchial calcifications had been anticoagulated with warfarin sodium between the time of surgery and development of positive imaging findings. Our findings suggest that tracheobronchial calcifications are not uncommon in children treated with warfarin. Further investigation is necessary to determine wether there is a cause–effect relationship in these children.
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References
Fukuya T, Mihara F, Kudo S et al (1989) Tracheobronchial calcification in members of a fixed population sample. Acta Radiol 30:277–280
Hatley W, Samuel E, Evison G (1965) The pattern of ossification in the laryngeal cartilages: a radiological study. Br J Radiol 38:585–591
Hoeffel JC, Bretagne MC, Thollot F (1988) Calcification of the laryngeal, tracheal, and bronchial cartilages in children. Am J Dis Child 142:1024–1026
Haddad MC, Sharif HS, Jared MS et al (1993) Premature tracheobronchial, laryngeal and costochondral cartilage calcification in children. Clin Radiol 47:52–55
Fryns JP, van Fleteren A, Mattelaer P et al (1984) Calcification of cartilages, brachytelephalangy and peripheral pulmonary stenosis. Confirmation of the Keutel syndrome. Eur J Pediatr 142:201–203
Andersen PE Jr, Justesen P (1987) Chondrodysplasia punctata. Report of two cases. Skeletal Radiol 16:223–226
Abbott A, Sibert JR, Weaver JB (1977) Chondrodysplasia punctata and maternal warfarin treatment. Br Med J 1:1639–1640
Thollot F, Hoeffel JC, Bretagne MC et al (1988) Idiopathic laryngotracheobronchial calcifications in children. Apropos of 2 cases. J Radiol 69:217–221
Taybi H, Capitanio MA (1990) Tracheobronchial calcification: an observation in three children after mitral valve replacement and warfarin sodium therapy. Radiology 176:728–730
Rifkin MD, Pritzker HA (1984) Tracheobronchial cartilage calcification in children. Case reports and review of the literature. Br J Radiol 57:293–296
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Golding, L.P., Walsh, M.J., Sumner, T.E. et al. Tracheobronchial calcifications in children. Pediatr Radiol 43, 937–940 (2013). https://doi.org/10.1007/s00247-013-2649-6
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DOI: https://doi.org/10.1007/s00247-013-2649-6