Abstract
Magnetic resonance imaging (MRI) is the modality of choice for determining the extent of a primary bone tumor. This article will discuss the MRI techniques needed to accurately define the intramedullary extent of a bone sarcoma, emphasizing the need for non-contrast T1-weighted sequences and highlighting the role of chemical shift imaging.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Verstraete KL, Lang P (2000) Bone and soft tissue tumors: the role of contrast agents for MR imaging. Eur J Radiol 34:229–246
Hwang S, Panicek DM (2007) Magnetic resonance imaging of bone marrow in oncology, Part 1. Skeletal Radiol 36:913–920
Gillespy T 3rd, Manfrini M, Ruggieri P et al (1988) Staging of intraosseous extent of osteosarcoma: correlation of preoperative CT and MR imaging with pathologic macroslides. Radiology 167:765–767
Onikul E, Fletcher BD, Parham DM et al (1996) Accuracy of MR imaging for estimating intraosseous extent of osteosarcoma. AJR Am J Roentgenol 167:1211–1215
Vogler JB 3rd, Murphy WA (1988) Bone marrow imaging. Radiology 168:679–693
Vanel D, Dromain C, Tardivon A (2000) MRI of bone marrow disorders. Eur Radiol 10:224–229
Kan J (2008) Major pitfalls in musculoskeletal imaging-MRI. Pediatr Radiol 38:251–255
Burdiles A, Babyn PS (2009) Pediatric bone marrow MR imaging. Magn Reson Imaging Clin N Am 17:391–409
Alyas F, Saifuddin A, Connell D (2007) MR imaging evaluation of the bone marrow and marrow infiltrative disorders of the lumbar spine. Magn Reson Imaging Clin N Am 15:199–219, vi
Nobauer I, Uffmann M (2005) Differential diagnosis of focal and diffuse neoplastic diseases of bone marrow in MRI. Eur J Radiol 55:2–32
Seeger LL, Widoff BE, Bassett LW et al (1991) Preoperative evaluation of osteosarcoma: value of gadopentetate dimeglumine-enhanced MR imaging. AJR Am J Roentgenol 157:347–351
Erlemann R, Reiser MF, Peters PE et al (1989) Musculoskeletal neoplasms: static and dynamic Gd-DTPA–enhanced MR imaging. Radiology 171:767–773
Disler DG, McCauley TR, Ratner LM et al (1997) In-phase and out-of-phase MR imaging of bone marrow: prediction of neoplasia based on the detection of coexistent fat and water. AJR Am J Roentgenol 169:1439–1447
Zampa V, Cosottini M, Michelassi C et al (2002) Value of opposed-phase gradient-echo technique in distinguishing between benign and malignant vertebral lesions. Eur Radiol 12:1811–1818
Eito K, Waka S, Naoko N et al (2004) Vertebral neoplastic compression fractures: assessment by dual-phase chemical shift imaging. J Magn Reson Imaging 20:1020–1024
Zajick DC Jr, Morrison WB, Schweitzer ME et al (2005) Benign and malignant processes: normal values and differentiation with chemical shift MR imaging in vertebral marrow. Radiology 237:590–596
Erly WK, Oh ES, Outwater EK (2006) The utility of in-phase/opposed-phase imaging in differentiating malignancy from acute benign compression fractures of the spine. AJNR Am J Neuroradiol 27:1183–1188
Ragab Y, Emad Y, Gheita T et al (2009) Differentiation of osteoporotic and neoplastic vertebral fractures by chemical shift in-phase and out-of phase MR imaging. Eur J Radiol 72:125–133
Costa FM, Canella C, Gasparetto E (2011) Advanced magnetic resonance imaging techniques in the evaluation of musculoskeletal tumors. Radiol Clin North Am 49:1325–1358, vii–viii
Teo HE, Peh WC (2004) The role of imaging in the staging and treatment planning of primary malignant bone tumors in children. Eur Radiol 14:465–475
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Shiga, N.T., Del Grande, F., Lardo, O. et al. Imaging of primary bone tumors: determination of tumor extent by non-contrast sequences. Pediatr Radiol 43, 1017–1023 (2013). https://doi.org/10.1007/s00247-012-2605-x
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00247-012-2605-x