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MRI for the diagnosis of recurrent middle ear cholesteatoma in children—can we optimize the technique? Preliminary study

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Abstract

Background

Recurrent cholesteatoma after surgical excision occurs frequently in children. Until recently, a surgical second look was mandatory and considered as standard reference. MRI including a delayed T1 sequence after gadolinium injection and diffusion-weighted imaging (DWI) has proved its efficiency but has been evaluated mainly in adults.

Objective

Our purpose was to evaluate the accuracy of DWI to diagnose recurrence of cholesteatoma in children.

Materials and methods

We evaluated prospectively with MRI 20 ears in 18 children who had had surgery for cholesteatoma. We compared DWI and delayed T1-weighted images following gadolinium administration with intraoperative or follow-up findings. We calculated the sensitivity and specificity of each sequence for the diagnosis of recurrent cholesteatoma.

Results

Sensitivity to diagnose recurrent cholesteatoma was 87% for both DWI and delayed post-gadolinium sequences, specificity was 71% and 83%, respectively. Adding both sequences, the sensitivity was 87%, the specificity 100%. There was one false negative probably due to small size recurrence.

Conclusion

In our series, DWI was reliable to diagnose recurrent cholesteatoma in children and allows avoiding surgery when negative. However, because small recurrences less than 5 mm may be missed, follow-up must be prolonged (5 years).

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Authors and Affiliations

  1. Fondation Lenval, 57 avenue de la Californie, 06200, Nice, France

    Anne Geoffray, Myriam Guesmi, Jean François Nebbia, Béatrice Leloutre, Sonanda Bailleux & Claude Maschi

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  1. Anne Geoffray
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  2. Myriam Guesmi
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  3. Jean François Nebbia
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Correspondence to Anne Geoffray.

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Geoffray, A., Guesmi, M., Nebbia, J.F. et al. MRI for the diagnosis of recurrent middle ear cholesteatoma in children—can we optimize the technique? Preliminary study. Pediatr Radiol 43, 464–473 (2013). https://doi.org/10.1007/s00247-012-2502-3

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  • DOI: https://doi.org/10.1007/s00247-012-2502-3

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