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MRI findings in multifetal pregnancies complicated by twin reversed arterial perfusion sequence (TRAP)

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Abstract

Background

Twin reversed arterial perfusion sequence (TRAP) is a rare complication in multifetal monochorionic pregnancies in which a normal “pump” twin provides circulation to an abnormal acardiac co-twin, resulting in high-output cardiac dysfunction in the pump twin.

Objective

To define fetal MRI findings of TRAP sequence.

Materials and methods

Fetal MR images were retrospectively reviewed in 35 pregnancies complicated by TRAP sequence. Abnormalities of the pump twin, acardiac twin, umbilical cord, placenta and amniotic fluid were reviewed.

Results

Acardiac twins were classified as: acephalus (51%), anceps (40%), amorphus (9%), acormus (0%). Common findings in acardiac twins include subcutaneous edema (77%), absent cardiac structures (86%), absent or abnormal thoracic cavity (100%), abnormal abdominal organs (100%), superior limbs absent (46%) or abnormal (51%), and inferior limbs present but abnormal (83%). There were pump twin findings of cardiac dysfunction in 43% and intracranial ischemic changes in 3%. Umbilical cord anomalies were present in 97%.

Conclusion

Acardiac twins present with a predictable pattern of malformation with poorly developed superior structures, more normally formed inferior structures and absent or rudimentary heart. Although usually absent, abnormal heart structures can be seen and do not exclude TRAP sequence. Pump twins are commonly normal with exception of findings of cardiac dysfunction and possible brain ischemia.

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Authors and Affiliations

  1. Department of Radiology, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave., MLC 5031, Cincinnati, OH, 45229-3039, USA

    Carolina V. A. Guimaraes, Beth M. Kline-Fath, Leann E. Linam, Maria A. Calvo Garcia & Eva I. Rubio

  2. Division of Pediatric Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    Foong-Yen Lim

Authors
  1. Carolina V. A. Guimaraes
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  2. Beth M. Kline-Fath
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  3. Leann E. Linam
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  4. Maria A. Calvo Garcia
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  5. Eva I. Rubio
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  6. Foong-Yen Lim
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Corresponding author

Correspondence to Carolina V. A. Guimaraes.

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Guimaraes, C.V.A., Kline-Fath, B.M., Linam, L.E. et al. MRI findings in multifetal pregnancies complicated by twin reversed arterial perfusion sequence (TRAP). Pediatr Radiol 41, 694–701 (2011). https://doi.org/10.1007/s00247-010-1921-2

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  • DOI: https://doi.org/10.1007/s00247-010-1921-2

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