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New MR sequences (diffusion, perfusion, spectroscopy) in brain tumours

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Abstract

While MRI has been instrumental in significantly improving care in children harbouring brain tumours, conventional sequences lack information regarding functional parameters including cellularity, haemodynamics and metabolism. Advanced MR imaging modalities, such as diffusion (including diffusion tensor imaging and fibre tractography), perfusion and spectroscopy have significantly improved our understanding of the physiopathology of brain tumours and have provided invaluable additional information for treatment planning and monitoring of treatment results. The contribution of these methods to the characterization of brain neoplasms in children is the focus of the present manuscript.

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Authors and Affiliations

  1. Pediatric Neuroradiology, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, Genova, 16147, Italy

    Andrea Rossi, Carlo Gandolfo, Giovanni Morana & Mariasavina Severino

  2. Pediatric Neuro-oncology, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, Genova, 16147, Italy

    Maria Luisa Garrè

  3. Pediatric Neurosurgery, G. Gaslini Children’s Research Hospital, Largo G. Gaslini 5, Genova, 16147, Italy

    Armando Cama

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  1. Andrea Rossi
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  2. Carlo Gandolfo
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  3. Giovanni Morana
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  4. Mariasavina Severino
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  5. Maria Luisa Garrè
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  6. Armando Cama
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Correspondence to Andrea Rossi.

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Rossi, A., Gandolfo, C., Morana, G. et al. New MR sequences (diffusion, perfusion, spectroscopy) in brain tumours. Pediatr Radiol 40, 999–1009 (2010). https://doi.org/10.1007/s00247-010-1613-y

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  • DOI: https://doi.org/10.1007/s00247-010-1613-y

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