Abstract
This article details indications, patient preparation, pulse sequences/protocols, and contrast agents for pediatric hepatobiliary MRI. When performed well, MRI provides superior diagnostic information relative to CT for evaluation of hepatic tumors, liver transplants, and biliary disease.
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Finn JP, Hall-Craggs MA, Dicks-Mireaux C et al (1990) Primary malignant liver tumors in childhood: assessment of resectability with high-field MR and comparison with CT. Pediatr Radiol 21:34–38
Semelka RC, Shoenut JP, Kroeker MA et al (1992) Focal liver disease: comparison of dynamic contrast-enhanced CT and T2-weighted fat-suppressed, FLASH, and dynamic gadolinium-enhanced MR imaging at 1.5 T. Radiology 184:687–694
Weinreb JC, Cohen JM, Armstrong E et al (1986) Imaging the pediatric liver: MRI and CT. Am J Roentgenol 147:785–790
Roebuck DJ, Aronson D, Clapuyt P et al (2007) 2005 PRETEXT: a revised staging system for primary malignant liver tumours of childhood developed by the SIOPEL group. Pediatr Radiol 37:123–132, quiz 149–150
Roebuck DJ, Olsen O, Pariente D (2006) Radiological staging in children with hepatoblastoma. Pediatr Radiol 36:176–182
Arcement CM, Meza MP, Arumanla S et al (2001) MRCP in the evaluation of pancreaticobiliary disease in children. Pediatr Radiol 31:92–97
Delaney L, Applegate KE, Karmazyn B et al (2008) MR cholangiopancreatography in children: feasibility, safety, and initial experience. Pediatr Radiol 38:64–75
Chavhan GB, Roberts E, Moineddin R et al (2008) Primary sclerosing cholangitis in children: utility of magnetic resonance cholangiopancreatography. Pediatr Radiol 38:868–873
Ferrara C, Valeri G, Salvolini L et al (2002) Magnetic resonance cholangiopancreatography in primary sclerosing cholangitis in children. Pediatr Radiol 32:413–417
Hamada Y, Tanano A, Takada K et al (2004) Magnetic resonance cholangiopancreatography on postoperative work-up in children with choledochal cysts. Pediatr Surg Int 20:43–46
Irie H, Honda H, Jimi M et al (1998) Value of MR cholangiopancreatography in evaluating choledochal cysts. Am J Roentgenol 171:1381–1385
Kim MJ, Han SJ, Yoon CS et al (2002) Using MR cholangiopancreatography to reveal anomalous pancreaticobiliary ductal union in infants and children with choledochal cysts. Am J Roentgenol 179:209–214
Krause D, Cercueil JP, Dranssart M et al (2002) MRI for evaluating congenital bile duct abnormalities. J Comput Assist Tomogr 26:541–552
Fishbein M, Castro F, Cheruku S et al (2005) Hepatic MRI for fat quantitation: its relationship to fat morphology, diagnosis, and ultrasound. J Clin Gastroenterol 39:619–625
Fishbein MH, Gardner KG, Potter CJ et al (1997) Introduction of fast MR imaging in the assessment of hepatic steatosis. Magn Reson Imaging 15:287–293
Qayyum A, Goh JS, Kakar S et al (2005) Accuracy of liver fat quantification at MR imaging: comparison of out-of-phase gradient-echo and fat-saturated fast spin-echo techniques—initial experience. Radiology 237:507–511
Yin M, Talwalkar JA, Glaser KJ et al (2007) Assessment of hepatic fibrosis with magnetic resonance elastography. Clin Gastroenterol Hepatol 5(1207–1213):e1202
Fujita T, Ito K, Honjo K et al (2002) Hepatic parenchymal enhancement in the cirrhotic liver: evaluation by triple-phase dynamic MRI. Abdom Imaging 27:29–33
Lee JK, Dixon WT, Ling D et al (1984) Fatty infiltration of the liver: demonstration by proton spectroscopic imaging. Preliminary observations. Radiology 153:195–201
Wood JC, Enriquez C, Ghugre N et al (2005) MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood 106:1460–1465
Dagia C, Ditchfield M (2008) 3 T MRI in paediatrics: challenges and clinical applications. Eur J Radiol 68:309–319
Schindera ST, Merkle EM, Dale BM et al (2006) Abdominal magnetic resonance imaging at 3.0 T what is the ultimate gain in signal-to-noise ratio? Acad Radiol 13:1236–1243
Runge VM, Clanton JA, Partain CL et al (1984) Respiratory gating in magnetic resonance imaging at 0.5 Tesla. Radiology 151:521–523
Kim BS, Kim JH, Choi GM et al (2008) Comparison of three free-breathing T2-weighted MRI sequences in the evaluation of focal liver lesions. Am J Roentgenol 190:W19–W27
Klessen C, Asbach P, Kroencke TJ et al (2005) Magnetic resonance imaging of the upper abdomen using a free-breathing T2-weighted turbo spin echo sequence with navigator triggered prospective acquisition correction. J Magn Reson Imaging 21:576–582
Lee SS, Byun JH, Hong HS et al (2007) Image quality and focal lesion detection on T2-weighted MR imaging of the liver: comparison of two high-resolution free-breathing imaging techniques with two breath-hold imaging techniques. J Magn Reson Imaging 26:323–330
Busse RF, Hariharan H, Vu A et al (2006) Fast spin echo sequences with very long echo trains: design of variable refocusing flip angle schedules and generation of clinical T2 contrast. Magn Reson Med 55:1030–1037
Hennig J, Weigel M, Scheffler K (2003) Multiecho sequences with variable refocusing flip angles: optimization of signal behavior using smooth transitions between pseudo steady states (TRAPS). Magn Reson Med 49:527–535
Kijowski R, Davis KW, Woods MA et al (2009) Knee joint: comprehensive assessment with 3D isotropic resolution fast spin-echo MR imaging—diagnostic performance compared with that of conventional MR imaging at 3.0 T. Radiology 252:486–495
Mugler JPK, Brookeman JR (2000) Three-dimensional T2-weighted imaging of the brain using very long spin-echo trains. International Society of Magnetic Resonance in Medicine 8th Meeting, Denver, CO, p 687
Nandalur KR, Hussain HK, Weadock WJ et al (2008) Possible biliary disease: diagnostic performance of high-spatial-resolution isotropic 3D T2-weighted MRCP. Radiology 249:883–890
Miyazaki T, Yamashita Y, Tang Y et al (1998) Single-shot MR cholangiopancreatography of neonates, infants, and young children. Am J Roentgenol 170:33–37
Carlos RC, Branam JD, Dong Q et al (2002) Biliary imaging with Gd-EOB-DTPA: is a 20-minute delay sufficient? Acad Radiol 9:1322–1325
Koelblinger C, Schima W, Weber M et al (2009) Gadoxate-enhanced T1-weighted MR cholangiography: comparison of 1.5 T and 3.0 T. Rofo 181:587–592
Lee NK, Kim S, Lee JW et al (2009) Biliary MR imaging with Gd-EOB-DTPA and its clinical applications. Radiographics 29:1707–1724
Seale MK, Catalano OA, Saini S et al (2009) Hepatobiliary-specific MR contrast agents: role in imaging the liver and biliary tree. Radiographics 29:1725–1748
Takao H, Akai H, Tajima T et al (2009) MR imaging of the biliary tract with Gd-EOB-DTPA: effect of liver function on signal intensity. Eur J Radiol Aug 31 [Epub ahead of print]
Maki JH, Wilson GJ, Eubank WB et al (2007) Steady-state free precession MRA of the renal arteries: breath-hold and navigator-gated techniques vs. CE-MRA. J Magn Reson Imaging 26:966–973
Katoh M, Buecker A, Stuber M et al (2004) Free-breathing renal MR angiography with steady-state free-precession (SSFP) and slab-selective spin inversion: initial results. Kidney Int 66:1272–1278
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Dr. Vasanawala has indicated that he has no relevant financial relationships or potential conflicts of interest related to the material presented.
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Vasanawala, S.S. MRI of the liver—how to do it. Pediatr Radiol 40, 431–437 (2010). https://doi.org/10.1007/s00247-009-1522-0
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DOI: https://doi.org/10.1007/s00247-009-1522-0