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Congenital tumours involving the head, neck and central nervous system

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Abstract

Congenital intracranial tumours are uncommon and differ from those occurring in older children in clinical presentation, imaging characteristics and prognosis. These tumours are often detected incidentally on routine prenatal US and/or fetal MRI. Hence, the paediatric radiologist should be familiar with the features of those lesions that should be included in the differential diagnosis. In general, the prognosis of these conditions is poor owing to large tumour size and the limitations of adjuvant therapy at such a young age. Congenital lesions involving the head and neck region require a meticulous imaging approach using both US and MRI techniques to better guide prenatal planning and fetal or neonatal surgical procedures.

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References

  1. Ainstein LH, Boldery E, Naffziger HC (1951) A case report and survey of brain tumors during the neonatal period. J Neurosurg 8:315–319

    Article  Google Scholar 

  2. Isaacs H Jr (2002) I Perinatal brain tumors: a review of 250 cases. Pediatr Neurol 27:249–261

    Article  PubMed  Google Scholar 

  3. Isaacs H Jr (2002) II Perinatal brain tumors: a review of 250 cases. Pediatr Neurol 27:333–342

    Article  PubMed  Google Scholar 

  4. Woodward PJ, Sohaey R, Kennedy A et al (2005) From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics 25:215–242

    Article  PubMed  Google Scholar 

  5. Solitare GB, Krigman MR (1964) Congenital intracranial neoplasm: a case report and review of the literature. J Neuropathol Exp Neurol 23:280–292

    Article  CAS  PubMed  Google Scholar 

  6. Jellinger K, Sunder-Plassmann M (1973) Connatal intracranial tumors. Neuropaediatrie 4:46–63

    Article  CAS  Google Scholar 

  7. Seker A, Ozek MM (2006) Congenital glioblastoma multiforme. Case report and review of the literature. J Neurosurg 105:473–479

    Google Scholar 

  8. Nejat F, Kazmi SS, Ardakani SB (2008) Congenital brain tumors in a series of seven patients. Pediatr Neurosurg 44:1–8

    Article  PubMed  Google Scholar 

  9. Chung SK, Wang KC, Nam DH et al (1998) Brain tumor in the first year of life; a single institute study. J Korean Med Sci 13:65–70

    CAS  PubMed  Google Scholar 

  10. Wakai S, Arai T, Nagai M (1984) Congenital brain tumors. Surg Neurol 21:597–609

    Article  CAS  PubMed  Google Scholar 

  11. Buetow PC, Smirniotopoulos JG, Done S (1990) Congenital brain tumors: a review of 45 cases. AJR 155:587–593

    CAS  PubMed  Google Scholar 

  12. Young HK, Johnston H (2004) Intracranial tumors in infants. J Child Neurol 19:424–430

    PubMed  Google Scholar 

  13. Levine D, Barnes PD, Robertson RR et al (2003) Fast MR imaging of fetal central nervous system abnormalities. Radiology 229:51–61

    Article  PubMed  Google Scholar 

  14. Sandow BA, Dory CE, Aguiar MA et al (2004) Best cases from the AFIP: congenital intracranial teratoma. Radiographics 24:1165–1170

    Article  PubMed  Google Scholar 

  15. Arslan E, Usul H, Baykal S et al (2007) Massive congenital intracranial immature teratoma of the lateral ventricle with retro-orbital extension: a case report and review of the literature. Pediatr Neurosurg 43:338–342

    Article  PubMed  Google Scholar 

  16. Rickert CH, Probst-Cousin S, Louwen F et al (1997) Congenital immature teratoma of the fetal brain. Childs Nerv Syst 13:556–559

    Article  CAS  PubMed  Google Scholar 

  17. Ortega-Aznar A, Romero-Vidal FJ, de la Torre J et al (2001) Neonatal tumors of the CNS: a report of 9 cases and a review. Clin Neuropathol 20:181–189

    CAS  PubMed  Google Scholar 

  18. Rickert CH, Göcke H, Paulus W (2002) Fetal ependymoma associated with Down’s syndrome. Acta neuropathol 103:78–81

    Article  PubMed  Google Scholar 

  19. Sato T, Shimoda A, Takahashi T et al (1984) Congenital anaplastic ependymoma: a case report of familial glioma. Childs Brain 11:342–348

    CAS  PubMed  Google Scholar 

  20. Dhillon G, Fratkin JD, Lancon JA et al (1998) One-day-old little girl with intermittent apnea. Pediatr Neurosurg 29:105–110

    Article  CAS  PubMed  Google Scholar 

  21. Yamada T, Takeuchi K, Masuda Y et al (2003) Prenatal imaging of congenital cerebral primitive neuroectodermal tumor. Fetal Diagn Ther 18:137–139

    Article  PubMed  Google Scholar 

  22. Sahin FK, Koken G, Cosar E et al (2008) A prenatal diagnosed case of primitive neuroectodermal tumor. Fetal Diagn Ther 23:267–270

    Article  PubMed  Google Scholar 

  23. Kan P, Liu JK, Hedlund G et al (2006) The role of diffusion-weighted magnetic resonance imaging in pediatric brain tumors. Childs Nerv Syst 22:1435–1439

    Article  PubMed  Google Scholar 

  24. Nishihira Y, Tan CF, Hirato J et al (2007) A case of congenital supratentorial tumor: atypical teratoid/rhabdoid tumor or primitive neuroectodermal tumor? Neuropathology 27:551–555

    Article  PubMed  Google Scholar 

  25. Horská A, Ulug AM, Melhem ER et al (2001) Proton magnetic resonance spectroscopy of choroid plexus tumors in children. J Magn Reson Imaging 14:78–82

    Article  PubMed  Google Scholar 

  26. Krieger MD, Panigrahy A, McComb JG et al (2005) Differentiation of choroid plexus tumors by advanced magnetic resonance spectroscopy. Neurosurg Focus 18:E4

    PubMed  Google Scholar 

  27. Cassart M, Bosson M, Garel C et al (2008) Fetal intracranial tumours: a review of 27 cases. Eur Radiol 18:2060–2066

    Article  CAS  PubMed  Google Scholar 

  28. Truwit CL, Barkovich AJ (1990) Pathogenesis of intracranial lipoma: a MR study in 42 patients. AJR 155:855–864

    CAS  PubMed  Google Scholar 

  29. Hashimoto H, Sakaki T, Ishida Y et al (1997) Fetal cavernous angioma. Case report. Neurol Med Chir 37:346–349

    Article  CAS  Google Scholar 

  30. Karmazyn B, Michovitz S, Sirota L et al (2001) Intracranial cavernous angioma in a neonate. Pediatric Radiol 31:610–612

    Article  CAS  Google Scholar 

  31. Karabagli H, Karabagli P, Alpman A et al (2007) Congenital supratentorial cystic hemangioblastoma. Case report and review of the literature. J Neurosurg 107:515–518

    Article  PubMed  Google Scholar 

  32. Garmel SH, Crombleholme TM, Semple JP et al (1994) Prenatal diagnosis and management of fetal tumors. Semin Perinatol 18:350–365

    CAS  PubMed  Google Scholar 

  33. Johnston JM, Vyas NA, Kane AA et al (2007) Giant intracranial teratoma with epignathus in a neonate. Case report and review of the literature. J Neurosurg 106:232–236

    PubMed  Google Scholar 

  34. Vandenhaute B, Leteurtre E, Lecomte-Houcke M et al (2000) Epignathus teratoma: report of three cases with a review of the literature. Cleft Palate Craniofac J 37:83–91

    Article  CAS  PubMed  Google Scholar 

  35. Hamon-Kérautret M, Ares GS, Demondion X et al (1998) Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal teratoma. Pediatr Radiol 28:290–292

    Article  PubMed  Google Scholar 

  36. Wagner W, Harrison MR (2002) Fetal operations in the head and neck area: current state. Head Neck 24:482–490

    Article  PubMed  Google Scholar 

  37. Stocks RM, Egerman RS, Woodson GE et al (1997) Airway management of neonates with antenatally detected head and neck anomalies. Arch Otolaryngol Head Neck Surg 123:641–645

    CAS  PubMed  Google Scholar 

  38. Hirose S, Farmer DL, Lee H et al (2004) The ex utero intrapartum treatment procedure: looking back at the EXIT. J Pediatr Surg 39:375–380

    Article  PubMed  Google Scholar 

  39. Bouchard S, Johnson MP, Flake AW et al (2002) The EXIT procedure: experience and outcome in 31 cases. J Pediatr Surg 37:418–426

    Article  PubMed  Google Scholar 

  40. Tekşam M, Ozyer U, McKinney A (2005) MR imaging and ultrasound of fetal cervical cystic lymphangioma: utility in antepartum treatment planning. Diagn Interv Radiol 11:87–89

    PubMed  Google Scholar 

  41. Kathary N, Bulas DI, Newman KD et al (2001) MRI imaging of fetal neck masses with airway compromise: utility in delivery planning. Pediatr Radiol 31:727–731

    Article  CAS  PubMed  Google Scholar 

  42. Gorincour G, Kokta V, Rypens F et al (2005) Imaging characteristics of two subtypes of congenital hemangiomas: rapidly involuting congenital hemangiomas and non-involuting congenital hemangiomas. Pediatr Radiol 35:1178–1185

    Article  PubMed  Google Scholar 

  43. Konez O, Burrows PE, Mulliken JB et al (2003) Angiographic features of rapidly involuting congenital hemangioma (RICH). Pediatr Radiol 33:15–19

    Article  PubMed  Google Scholar 

  44. Brix M, Soupre V, Enjolras O et al (2007) Antenatal diagnosis of rapidly involuting congenital hemangiomas (RICH). Rev Stomatol Chir Maxillofac 108:109–114

    CAS  PubMed  Google Scholar 

  45. Elia D, Garel C, Enjolras O et al (2008) Prenatal imaging findings in rapidly involuting congenital hemangioma of the skull. Ultrasound Obstet Gynecol 31:572–575

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

The authors thank Dr. Nuria Toran for providing the histopathological material and Celine Cavallo for English language editing.

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Correspondence to Elida Vazquez.

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Vazquez, E., Castellote, A., Mayolas, N. et al. Congenital tumours involving the head, neck and central nervous system. Pediatr Radiol 39, 1158–1172 (2009). https://doi.org/10.1007/s00247-009-1369-4

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  • DOI: https://doi.org/10.1007/s00247-009-1369-4

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