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Pediatric littoral cell angioma of the spleen: multimodality imaging including diffusion-weighted imaging

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Abstract

Littoral cell angioma (LCA) is a rare primary splenic vascular tumor originating from littoral cells lining the splenic red pulp sinuses. LCAs are rarely seen in children. We present the US, CT, and MRI findings including diffusion-weighted imaging (DWI) in a 2-year-old boy with histologically proven LCA. Previous studies on liver lesions have shown that DWI allows differentiation of vascular tumors from primary neoplasms and metastatic disease. The current case indicates that increased ADC values within the splenic lesions suggest a vascular etiology, which might help narrow the differential diagnosis.

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Authors and Affiliations

  1. Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, 600 N. Wolfe St., Nelson Basement, B-173, Baltimore, MD, 21287-0842, USA

    Gulhan Ertan, Aylin Tekes & Thierry A. G. M. Huisman

  2. Division of Cardiovascular and Interventional Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USA

    Sally Mitchell

  3. Division of Pediatric Hematology, Department of Pediatrics, Johns Hopkins Hospital, Baltimore, MD, USA

    Jeffrey Keefer

Authors
  1. Gulhan Ertan
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  2. Aylin Tekes
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  3. Sally Mitchell
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  4. Jeffrey Keefer
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  5. Thierry A. G. M. Huisman
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Corresponding author

Correspondence to Thierry A. G. M. Huisman.

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Ertan, G., Tekes, A., Mitchell, S. et al. Pediatric littoral cell angioma of the spleen: multimodality imaging including diffusion-weighted imaging. Pediatr Radiol 39, 1105–1109 (2009). https://doi.org/10.1007/s00247-009-1339-x

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  • DOI: https://doi.org/10.1007/s00247-009-1339-x

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