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The blood supply of early, late, and nonossifying cartilage: preliminary gray-scale and Doppler assessment and their implications

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Abstract

Background

Comparative gray-scale Doppler US studies of various cartilages have not been reported before.

Objective

To study gray-scale US and perfusion patterns of different cartilages.

Materials and methods

Three groups of cartilages were studied in 42 normal neonates. Group A included the proximal femoral chondroepiphysis of 20 neonates as well as proximal humeral, distal femoral, and proximal tibial epiphyses of 8 others. Group B included the patellar cartilage of nine neonates and group C included the rib cartilage of five neonates.

Results

Early ossifying cartilages all had numerous echogenic columns on US. Late ossifying patellar cartilage was amorphous and hypoechoic at birth but contained echogenic columns near the ossification age. Rib cartilage was hypoechoic and amorphous at all ages. The blood supply was detectable in all cartilages except the ribs. Peak systolic velocities increased with age in the proximal femoral epiphysis. The patellar cartilage was less vascular than the distal femoral epiphysis at birth, but more vascular at 14–24 months of age. The rib cartilage did not have any discernable blood supply at any age.

Conclusions

Cartilage blood flow is detectable with current technology. Cartilage blood flow correlates with the timing of its ossification. Normal cartilage blood flow may prognosticate normality of its growth and development potential.

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Authors and Affiliations

  1. Department of Radiology, Section of Pediatric Radiology, The University of Chicago, 5841 S. Maryland Avenue, Chicago, IL, 60637, USA

    D. K. Yousefzadeh

  2. Radiology Associates of Northern Kentucky, Crestview Hills, KY, USA

    K. Doerger

  3. Department of Surgery, The University of Chicago, Chicago, IL, USA

    C. Sullivan

Authors
  1. D. K. Yousefzadeh
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  2. K. Doerger
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  3. C. Sullivan
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Corresponding author

Correspondence to D. K. Yousefzadeh.

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Yousefzadeh, D.K., Doerger, K. & Sullivan, C. The blood supply of early, late, and nonossifying cartilage: preliminary gray-scale and Doppler assessment and their implications. Pediatr Radiol 38, 146–158 (2008). https://doi.org/10.1007/s00247-007-0655-2

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  • DOI: https://doi.org/10.1007/s00247-007-0655-2

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