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Pediatric Radiology

, Volume 37, Issue 8, pp 734–738 | Cite as

Diffusion-weighted imaging in diagnosing neurological disorders in children: a pediatric neurologist’s perspective

  • Susan L. BenedictEmail author
Minisymposium

Abstract

Diffusion-weighted imaging (DWI) has provided a way to measure early changes in cellular function in the central nervous system. It has permitted rapid, less invasive diagnosis and treatment of neurological disorders that were once thought to be untreatable. DWI has also created new avenues of research and alternative ways to measure study outcomes. Seven clinical cases illustrate how DWI enhances the ability of the pediatric neurologist to rapidly diagnose acute neurological disorders in infants and children.

Keywords

Diffusion-weighted imaging MRI Children 

References

  1. 1.
    Le Bihan D, Breton E, Lallemand D et al (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161:401–407PubMedGoogle Scholar
  2. 2.
    Beaulieu C, D’Arceuil H, Hedehus M et al (1999) Diffusion-weighted magnetic resonance imaging: theory and potential applications to child neurology. Semin Pediatr Neurol 6:87–100PubMedCrossRefGoogle Scholar
  3. 3.
    Warch S, Chien D, Li W et al (1992) Fast magnetic resonance diffusion-weighted imaging of acute human stroke. Neurology 42:1717–1723Google Scholar
  4. 4.
    Cowan FM, Pennock JM, Hanrahan JD et al (1994) Early detection of cerebral infarction and hypoxic ischemic encephalopathy in neonates using diffusion-weighted magnetic resonance imaging. Neuropediatrics 25:172–175PubMedGoogle Scholar
  5. 5.
    Connelly A, Chong WK, Johnson CL et al (1997) Diffusion-weighted magnetic resonance imaging of compromised tissue in stroke. Arch Dis Child 77:38–41PubMedCrossRefGoogle Scholar
  6. 6.
    Ment LR, Bada HS, Barnes P et al (2002) Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 25:1726–1738Google Scholar
  7. 7.
    Takeoka M, Soman TB, Yoshii A et al (2002) Diffusion-weighted images in neonatal cerebral hypoxic-ischemic injury. Pediatr Neurol 26:274–281PubMedCrossRefGoogle Scholar
  8. 8.
    Monagle P, Chan AK, deVeber G et al (2006) Diagnosis of arterial ischemic stroke. In: Andrew’s pediatric thromboembolism and stroke. BC Decker, HamiltonGoogle Scholar
  9. 9.
    Lim CC, Lee W, Chung SM et al (2003) Diffusion-weighted MR imaging in intracranial infections. Ann Acad Med Singapore 32:446–449PubMedGoogle Scholar
  10. 10.
    Sener RN (2001) Herpes simplex encephalitis: diffusion MR imaging findings. Comput Med Imaging Graph 25:391–397PubMedCrossRefGoogle Scholar
  11. 11.
    Chu K, Kang D, Yoon B et al (2001) Diffusion-weighted magnetic resonance in cerebral venous thrombosis. Arch Neurol 58:1569–1575PubMedCrossRefGoogle Scholar
  12. 12.
    Benedict SL, Bonkowsky JL, Thompson JA et al (2004) Cerebral sinovenous thrombosis in children: another reason to treat iron deficiency anemia. J Child Neurol 19:526–531PubMedGoogle Scholar
  13. 13.
    Rovaris M, Gass A, Bammer R et al (2005) Diffusion MRI in multiple sclerosis. Neurology 65:1526–1532PubMedCrossRefGoogle Scholar
  14. 14.
    Gelal FM, Grant PE, Fischbein NJ et al (2001) The role of isotropic diffusion MRI in children under 2 years of age. Eur Radiol 11:1006–1014PubMedCrossRefGoogle Scholar
  15. 15.
    Ashwal S, Holshouser BA, Tong KA (2006) Use of advanced neuroimaging techniques in the evaluation of pediatric traumatic brain injury. Dev Neurosci 28:309–326PubMedCrossRefGoogle Scholar
  16. 16.
    Kan P, Liu JK, Hedlund G et al (2006) The role of diffusion-weighted magnetic resonance imaging in pediatric brain tumors. Childs Nerv Syst 22:1435–1439PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.Division of Pediatric NeurologyThe University of UtahSalt Lake CityUSA

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