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Primary cerebral leiomyosarcoma in a child

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Abstract

We present a 13-year-old boy with a low-grade primary intra-axial cerebral leiomyosarcoma. MRI showed a contrast-enhancing intra-axial mass with features of a cell-rich tumour. The diagnosis was established after neurosurgery and exclusion of an extracerebral primary tumour. The resection of local recurrence 6 months later confirmed the diagnosis, but a higher grade of malignancy was established. The patient died 15 months after the onset of symptoms from general intracranial and intraspinal spread.

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References

  1. Paulus W, Slowik F, Jellinger K (1991) Primary intracranial sarcomas: histopathological features of 19 cases. Histopathology 18:395–402

    CAS  PubMed  Google Scholar 

  2. Lee TT, Page LK (1997) Primary cerebral leiomyosarcoma. Clin Neurol Neurosurg 99:210–212

    Article  CAS  PubMed  Google Scholar 

  3. Brown HG, Burger PC, Olivi A, et al (1999) Intracranial leiomyosarcoma in a patient with AIDS. Neuroradiology 41:35–39

    Article  CAS  PubMed  Google Scholar 

  4. Litofsky NS, Pihan G, Corvi F, et al (1998) Intracranial leiomyosarcoma: a neuro-oncological consequence of acquired immunodeficiency syndrome. J Neurooncol 40:179–183

    Article  CAS  PubMed  Google Scholar 

  5. Louis DN, Richardson EP Jr, Dickersin GR, et al (1989) Primary intracranial leiomyosarcoma. Case report. J Neurosurg 71:279–282

    CAS  PubMed  Google Scholar 

  6. Feigin I, Allen L, Lipkon L, et al (1957) The endothelial hyperplasia of the cerebral blood vessels with brain tumors, and its sarcomatous transformation. Cancer 11:264–277

    Google Scholar 

  7. Mierau GW, Greffe BS, Weeks DA (1997) Primary leiomyosarcoma of brain in an adolescent with common variable immunodeficiency syndrome. Ultrastruct Pathol 21:301–305

    CAS  PubMed  Google Scholar 

  8. Lack EE (1986) Leiomyosarcomas in childhood: a clinical and pathologic study of 10 cases. Pediatr Pathol 6:181–197

    CAS  PubMed  Google Scholar 

  9. Pautier P, Genestie C, Rey A, et al (2000) Analysis of clinicopathologic prognostic factors for 157 uterine sarcomas and evaluation of a grading score validated for soft tissue sarcoma. Cancer 88:1425–1431

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Radiology Institute, Kantonsspital Winterthur, Brauerstrasse 15, 8401 Winterthur, Switzerland

    Boris P. Eckhardt, Christoph L. Zollikofer & Klaus U. Wentz

  2. MRC Prion Unit and Department of Neuropathology, Institute of Neurology, London, UK

    Sebastian Brandner

Authors
  1. Boris P. Eckhardt
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  2. Sebastian Brandner
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  3. Christoph L. Zollikofer
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  4. Klaus U. Wentz
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Corresponding author

Correspondence to Klaus U. Wentz.

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Eckhardt, B.P., Brandner, S., Zollikofer, C.L. et al. Primary cerebral leiomyosarcoma in a child. Pediatr Radiol 34, 495–498 (2004). https://doi.org/10.1007/s00247-003-1123-2

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  • DOI: https://doi.org/10.1007/s00247-003-1123-2

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