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Renal cell carcinoma in long-term survivors of advanced stage neuroblastoma in early childhood

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Abstract

Background

Renal cell carcinoma (RCC) is rare in children and comprises only 1–3% of all pediatric primary renal tumors. Recently, several case reports have described RCC developing in patients previously treated for advanced stage neuroblastoma (NB).

Methods and results

Our experience with four patients treated for advanced stage NB during early childhood who developed RCC later in life are added to 14 others in the literature.

Conclusion

These patients and our review of the literature suggest an association between RCC and NB that warrants further study.

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Acknowledgements

The authors would like to thank The Brent Eley Foundation for its generous support.

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Correspondence to Julie M. Fleitz.

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Fleitz, J.M., Wootton-Gorges, S.L., Wyatt-Ashmead, J. et al. Renal cell carcinoma in long-term survivors of advanced stage neuroblastoma in early childhood. Pediatr Radiol 33, 540–545 (2003). https://doi.org/10.1007/s00247-003-0913-x

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  • DOI: https://doi.org/10.1007/s00247-003-0913-x

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