Abstract
Background
Studies on dextrocardia have been limited by low numbers. Hence, it is very difficult to find the most common diagnosis in patients with dextrocardia, who are seeking medical attention in tertiary care center.
Aims and Objective
To identify the most common diagnostic pattern in patients with dextrocardia with different situs.
Methods
It is a retrospective study with records dating back to up to last 21 years from a major tertiary care center in south India. All the patients with diagnosis of dextrocardia (defined as right-sided baso-apical axis of heart) will be included in the study. Segmental analysis will be done as defined previously.
Results
There were total of n = 378 patients with dextrocardia, 43.3% were females and median age was 1 year while mean age was 7 years. Situs solitus was present in 43.1%, Situs inversus in 38.1%, and Situs ambiguus in 18.8%. In patients with situs solitus and dextrocardia, the most common diagnosis was congenitally corrected TGA ± PS/PA followed by Double outlet Right ventricle ± PS/PA; whereas in patients with Situs inversus and dextrocardia, the most common diagnosis was Double outlet Right ventricle ± PS/PA followed by normal hearts and Left to right shunts.
Conclusion
In patients with dextrocardia who are seeking medical advice in a tertiary care center, they are more likely to have situs solitus followed by situs inversus. In situs solitus atrio-ventricular discordance with right ventricular outflow obstruction is the most common lesion suggesting l-looping is the most predominant mechanism. In patients with situs inversus, DORV with RVOTO is the most common lesion.
Similar content being viewed by others
Abbreviations
- ASD :
-
Atrial septal defect
- CC-TGA :
-
Congenitally corrected transposition of great arteries
- CT :
-
Computed tomography
- DORV :
-
Double outlet right ventricle
- LV :
-
Left ventricle
- MR :
-
Magnetic resonance
- NRGA :
-
Normally related great arteries
- PA :
-
Pulmonary atresia
- PDA :
-
Patent ductus arteriosus
- PS :
-
Pulmonary stenosis
- RV :
-
Right ventricle
- RVOTO :
-
Right ventricular outflow tract obstruction
- TGA :
-
Transposition of great arteries
- VSD :
-
Ventricular septal defect
References
Walmsley R, Hishitani T, Sandor GGS, Lim K, Duncan W, Tessier F et al (2004) Diagnosis and outcome of dextrocardia diagnosed in the fetus. Am J Cardiol 94(1):141–143
Bohun CM, Potts JE, Casey BM, Sandor GGS (2007) A population-based study of cardiac malformations and outcomes associated with dextrocardia. Am J Cardiol 100(2):305–309
Calcaterra G, Anderson RH, Lau KC, Shinebourne EA (1979) Dextrocardia—value of segmental analysis in its categorisation. Br Heart J 42(5):497–507
Garg N, Agarwal BL, Modi N, Radhakrishnan S, Sinha N (2003) Dextrocardia: an analysis of cardiac structures in 125 patients. Int J Cardiol 88(2–3):143–155
Arcilla RA, Gasul BM (1961) Congenital dextrocardia. Part 2. J Pediatr 58(2):251–262
Van Praagh R, Van Praagh S, Vlad P, Keith JD (1964) Anatomic types of congenital dextrocardia. Am J Cardiol 13(4):510–531
Ellis K, Fleming RJ, Griffiths SP, Jameson AG (1966) New concepts in dextrocardia. Am J Roentgenol 97(2):295–313
Lev M, Liberthson RR, Eckner FAO, Arcilla RA (1968) Pathologic anatomy of dextrocardia and its clinical implications. Circulation 37(6):979–999
Squarcia U, Ritter DG, Kincaid OW (1973) Dextrocardia: angiocardiographic study and classification. Am J Cardiol 32(7):965–977
Licata RH (1954) The human embryonic heart in the ninth week. Am J Anat 94(1):73–125
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that they have no conflict of interest.
Ethical Approval
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed Consent
For this type of study, formal consent is not required (in view of the retrospective nature of the study).
Rights and permissions
About this article
Cite this article
Tripathi, S., Ajit Kumar, V.K. Comparison of Morphologic Findings in Patients with Dextrocardia with Situs Solitus vs Situs Inversus: a Retrospective Study. Pediatr Cardiol 40, 302–309 (2019). https://doi.org/10.1007/s00246-018-2007-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00246-018-2007-4