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Combined aspiration thrombectomy and continuous intrasinus thrombolysis for cerebral venous sinus thrombosis: technical note and case series

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A Letter to the Editor to this article was published on 05 June 2019

A Letter to the Editor to this article was published on 29 May 2019

Abstract

Cerebral venous sinus thrombosis is an uncommon cause of stroke with high morbidity and mortality rates from venous infarction, intracranial hemorrhage, and extensive cerebral edema. Endovascular treatment with various devices has been proposed as a salvage treatment when standard medical treatment with systemic anticoagulation is ineffective, especially in long segment dural sinus thrombosis. We describe our technique of transvenous endovascular aspiration thrombectomy with large bore thrombectomy catheters, followed by placement of microcatheter for local thrombolytic infusion at the site of thrombosis. We report a retrospective study of angiographic and clinical outcome of six consecutive patients treated with this approach. Endovascular aspiration thrombectomy with large bore catheters followed by continuous local thrombolytic infusion appeared to be a safe and effective salvage treatment for selected patients with cerebral dural venous sinus thrombosis refractory to medical treatment.

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Authors and Affiliations

  1. Division of Neurosurgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, Hong Kong

    Anderson Chun On Tsang, R. H. Y. Chiu, D. Y. C. Chan, F. C. P. Tsang, W. S. Ho, G. K. K. Leung & W. M. Lui

  2. Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong

    A. C. Hwang

  3. Department of Diagnostic Radiology, Queen Mary Hospital, Pok Fu Lam, Hong Kong

    R. Lee

Authors
  1. Anderson Chun On Tsang
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  2. A. C. Hwang
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  3. R. H. Y. Chiu
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  4. D. Y. C. Chan
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  5. F. C. P. Tsang
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  6. W. S. Ho
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  7. R. Lee
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  8. G. K. K. Leung
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  9. W. M. Lui
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Correspondence to Anderson Chun On Tsang.

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No funding was received for this study.

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The authors declare that they have no conflict of interest.

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All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

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For this type of retrospective study formal consent is not required.

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Tsang, A.C.O., Hwang, A.C., Chiu, R.H.Y. et al. Combined aspiration thrombectomy and continuous intrasinus thrombolysis for cerebral venous sinus thrombosis: technical note and case series. Neuroradiology 60, 1093–1096 (2018). https://doi.org/10.1007/s00234-018-2084-3

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  • DOI: https://doi.org/10.1007/s00234-018-2084-3

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