European Journal of Clinical Pharmacology

, Volume 74, Issue 2, pp 181–182 | Cite as

Pericarditis associated with cytarabine therapy for acute myelocytic leukemia: a case report

  • Xia Yang
  • Wei Liu
  • Allie Lyons
  • Zaiwei Song
  • Suodi Zhai
  • Kai Hu
Special Article



The incidence of cytarabine-induced pericarditis is rare. So far, only a few cases have been reported worldwide.

Description of the case

We are reporting a case of a 25-year-old male with acute myeloid leukemia (AML M2a) on chemotherapy who developed acute pericarditis after the administration of a cytarabine-containing regimen. The symptoms gradually improved after symptomatic treatment with steroids and other drugs.


This case demonstrates that, although pericarditis induced by cytarabine is rare, early recognition of this potentially life-threatening complication and appropriate management will usually result in the patient’s recovery.


Cytarabine Acute myeloid leukemia Pericarditis 

Supplementary material

228_2017_2355_MOESM1_ESM.docx (15 kb)
ESM 1 (DOCX 14 kb)


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • Xia Yang
    • 1
  • Wei Liu
    • 1
    • 2
  • Allie Lyons
    • 1
    • 3
  • Zaiwei Song
    • 1
  • Suodi Zhai
    • 1
    • 2
  • Kai Hu
    • 4
  1. 1.Department of PharmacyPeking University Third HospitalBeijingChina
  2. 2.Therapeutic Drug Monitoring and Clinical Toxicology CenterPeking UniversityBeijingChina
  3. 3.College of PharmacyUniversity of KentuckyLexingtonUSA
  4. 4.Department of HematologyPeking University Third HospitalBeijingChina

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