Abstract
Estrone, β-estradiol and ethynylestradiol spiked in water were extracted using solid-phase extraction (SPE) and then directly determined by micellar electrokinetic chromatography (MEKC) with online concentration (sweeping). A 350 mL original sample volume (10 nM each) was concentrated to 1 mL using SPE, and ca. 240 nL of this solution was injected onto an MEKC capillary column. After sweeping, the estrogen related compounds were detected using a commercial absorbance detection system with an LOD of 0.16–0.30 nM in the original sample.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 15 September 2000 / Revised: 16 November 2000 / Accepted: 20 November 2000
Rights and permissions
About this article
Cite this article
Harino, H., Tsunoi, S., Sato, T. et al. Applicability of micellar electrokinetic chromatography to the analysis of estrogens in water. Fresenius J Anal Chem 369, 546–547 (2001). https://doi.org/10.1007/s002160000671
Issue Date:
DOI: https://doi.org/10.1007/s002160000671