Highly sensitive electrochemical BPA sensor based on titanium nitride-reduced graphene oxide composite and core-shell molecular imprinting particles

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Abstract

A sensitive electrochemical sensor was proposed via combining molecular imprinting technique with the graphene material-doped titanium nitride. The novel graphene with 3-dimensional structure displayed more binding sites and better electrochemical properties. Moreover, this study focused on coating pyrrole with electrical conductivity on the surface of silica as a monomer, and BPA as the template. The interaction made specific detection possible, between monomer and template. With a series of characterizations and electrochemical measurements, CPE (carbon paste electrode)-contained TiN-rGO composite was proved to have conductivity improved. Also, the modified polymer performed well selectivity which reflected in that it was almost impervious to distractions. Under optimized conditions, a linear dependence was observed from 0.5 to 100 nmol L−1 with a detection limit of 0.19 nmol L−1. The sensor explicated outstanding repeatability via repetitive experiment with the RSD of 0.02%, while the results of stability experiment reached the RSD of 1.90%. Eventually, it was used to analyze BPA residues in 3 kinds of daily supplies. The results indicated the potential of the sensor in environmental detection prospectively.

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  • 03 December 2020

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Funding

This work was financially supported by the National Natural Science Foundation of China (No. 21677064), Science and Technology Planning Social Development Project of Jiangsu Province (No. BE2018694), Science and Technology Planning Social Development Project of Zhenjiang City (Nos. SH2018015, SH2019013), the Fifth phase “169 Project” training fund of Zhenjiang and Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment.

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Correspondence to Xiaoni Ni or Weihong Huang.

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Xu, W., Zhang, Y., Yin, X. et al. Highly sensitive electrochemical BPA sensor based on titanium nitride-reduced graphene oxide composite and core-shell molecular imprinting particles. Anal Bioanal Chem 413, 1081–1090 (2021). https://doi.org/10.1007/s00216-020-03069-7

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Keywords

  • Titanium nitride
  • Reduced graphene oxide
  • Polypyrrole
  • Molecular imprinting
  • Electrochemical sensor