Analytical and Bioanalytical Chemistry

, Volume 410, Issue 8, pp 2053–2057 | Cite as

The 2017 Nobel Prize in Chemistry: cryo-EM comes of age

  • Peter S. Shen
Feature Article


The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for “developing cryo-electron microscopy (cryo-EM) for the high-resolution structure determination of biomolecules in solution.” This feature article summarizes some of the major achievements leading to the development of cryo-EM and recent technological breakthroughs that have transformed the method into a mainstream tool for structure determination.


Cryo-EM Nobel Prize Structural biology TEM 


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of BiochemistryUniversity of UtahSalt Lake CityUSA

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