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The 2017 Nobel Prize in Chemistry: cryo-EM comes of age

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Abstract

The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank, and Richard Henderson for “developing cryo-electron microscopy (cryo-EM) for the high-resolution structure determination of biomolecules in solution.” This feature article summarizes some of the major achievements leading to the development of cryo-EM and recent technological breakthroughs that have transformed the method into a mainstream tool for structure determination.

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Authors and Affiliations

  1. Department of Biochemistry, University of Utah, Salt Lake City, UT, 84112, USA

    Peter S. Shen

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  1. Peter S. Shen
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Correspondence to Peter S. Shen.

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Shen, P.S. The 2017 Nobel Prize in Chemistry: cryo-EM comes of age. Anal Bioanal Chem 410, 2053–2057 (2018). https://doi.org/10.1007/s00216-018-0899-8

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  • DOI: https://doi.org/10.1007/s00216-018-0899-8

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