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Clinical and urodynamic differences among women with overactive bladder according to the presence of detrusor overactivity

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Abstract

Introduction and hypothesis

We tried to determine whether clinical and urodynamic differences exist between women with and without detrusor overactivity (DO) using a large database of overactive bladder (OAB) patients.

Methods

We reviewed the medical records of 513 women who underwent urodynamic studies for OAB symptoms without neurogenic or anatomical conditions that affect micturition function. Clinical symptoms were evaluated using a 3-day frequency-volume chart (FVC) including the Urinary Sensation Scale and American Urological Association Symptom Index (AUA-SI). All clinical and urodynamic findings were compared between women with and without DO.

Results

The patients’ mean age was 58.9 years. DO was identified urodynamically in 167 (32.6 %) women. Those with DO were older (62.9 vs 57.0 years, p < 0.001); however, no differences in AUA-SI, episodes of daytime voiding, and episodes of nocturia were observed between the groups. Functional bladder capacity was smaller in women with DO; however, this difference did not reach statistical significance. Women with DO had significantly more urgency incontinence symptoms than those without DO (55.1 vs 29.5 %, p < 0.001). In urodynamic parameters, the volumes at first desire to void and strong desire to void and maximum cystometric capacity were significantly smaller, and detrusor pressure at the opening was significantly higher in women with DO compared to subjects without DO (26.2 vs 21.2 cmH2O, p = 0.004).

Conclusions

Our findings suggest a more severe disturbance of bladder function when DO exists, although no differences were observed in symptom scores and 3-day FVC parameters among women with OAB symptoms according to the presence of DO.

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Acknowledgments

The authors would like to acknowledge Dr. Byung Ki Lee and Jong Jin Oh for their contributions to this study as advisors for medical writing. This study was supported by a grant from Seoul National University Bundang Hospital Research Fund.

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Authors and Affiliations

  1. Department of Urology, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam, 463-707, Korea

    Seong Jin Jeong, Sang Cheol Lee, Chang Wook Jeong, Sung Kyu Hong, Seok-Soo Byun & Sang Eun Lee

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  1. Seong Jin Jeong
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  2. Sang Cheol Lee
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Correspondence to Sang Eun Lee.

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Jeong, S.J., Lee, S.C., Jeong, C.W. et al. Clinical and urodynamic differences among women with overactive bladder according to the presence of detrusor overactivity. Int Urogynecol J 24, 255–261 (2013). https://doi.org/10.1007/s00192-012-1817-9

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  • DOI: https://doi.org/10.1007/s00192-012-1817-9

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