Abstract
Purpose
To examine implant migration and articular behavior of primary total knee arthroplasty (TKA) at 10 years after index surgery and correlate to implant alignment.
Methods
Thirty-five patients underwent a cemented posterior stabilized total knee arthroplasty with a surgical objective of neutral alignment and were enrolled in a long-term radiostereometric analysis (RSA) study. At 10 years after surgery, patients were analyzed for implant migration using RSA as well as radiographic assessment of articular behavior at four positions of knee flexion. Implant position and alignment was measured on full-length radiographs. Patient demographics and reported outcomes were also collected.
Results
No difference between patient demographics or patient-reported outcomes were found. When categorized into neutral and varus groupings, no difference in migration was present. If alignment was considered as a continuous variable, there was no correlation between overall leg alignment and migration, however, migration increased with an increasing varus tibial alignment. Although contact location did not differ between neutral and varus groups through a range of motion, condylar liftoff was much more common in the varus group, of which all were lateral liftoff.
Conclusions
Increased tibial varus results in increased implant migration. Overall varus limb alignment is correlated with isolated lateral compartment liftoff, and liftoff occurs more commonly than in neutral aligned knees. The increased migration and liftoff raise concerns about the longevity of malaligned total knee replacements. If a goal of overall varus limb alignment is desired for TKA, the tibia should remain neutral.
Level of evidence
Level III.
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MGT participated in the design of the study, conducted the statistical analysis, and co-wrote the initial manuscript draft. DDN, RWM, DWH, and SJM conceived of the initial migration study and collected the data. XY collected patient images and analyzed the data. BAL participated in the design of the study, collected the alignment data, and co-wrote the initial manuscript draft. All authors read and approved the final manuscript.
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Conflict of interest
One of the authors (DDN) is a paid consultant to Microport, Smith & Nephew, and Zimmer Biomet, and receives royalties from Smith & Nephew. One of the authors (RWM) is a paid consultant to Smith & Nephew. One of the authors (SJM) is a paid consultant to DePuy. One of the authors (BAL) is a paid consultant to DePuy, Smith & Nephew, and Stryker.
Funding
Smith & Nephew provided research funds in support of the study, but were not involved in study design or data analysis.
Ethical approval
The study was approved by the ethics committee of the institution.
Informed consent
Patients were informed, and they contented to conduct the study.
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Teeter, M.G., Naudie, D.D., McCalden, R.W. et al. Varus tibial alignment is associated with greater tibial baseplate migration at 10 years following total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 26, 1610–1617 (2018). https://doi.org/10.1007/s00167-017-4765-6
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DOI: https://doi.org/10.1007/s00167-017-4765-6