Paediatric acute kidney injury: can we match therapy with resources around the world?

  • Akash Deep
  • Jordan M. Symons
  • Mignon McCulloch
What's New in Intensive Care

Acute kidney injury (AKI) is a global public health problem with high rates of morbidity and mortality. In 2014, the International Society of Nephrology (ISN) conducted the Global Snapshot of AKI [1], demonstrating that the burden of AKI falls disproportionately on low- and lower-middle income countries (LLMICs), with increased levels of mortality compared to high-income countries (HICs). The Global Snapshot further revealed that nearly 10% of patients in need of renal replacement therapy (RRT) did not receive it. In addition to the lack of resources to diagnose and an inability to afford the therapy, there was also a scarcity of data addressing the epidemiology and causes of AKI in developing countries and poor awareness of the impact of AKI on patient outcomes. ISN has developed the 0 by 25 initiative to address this worldwide concern with the goal that by 2025, no one would die of preventable and treatable AKI.

Children are not exempt from AKI risks. The AWARE [2] and AWAKEN [3]...


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Conflicts of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature and ESICM 2018

Authors and Affiliations

  • Akash Deep
    • 1
  • Jordan M. Symons
    • 2
  • Mignon McCulloch
    • 3
  1. 1.Chair of Renal/CRRT section of ESPNICConsultant Intensivist, King’s College HospitalLondonUK
  2. 2.Seattle Children’s HospitalUniversity of Washington School of MedicineSeattleUSA
  3. 3.Red Cross War Memorial Children’s HospitalUniversity of Cape TownCape TownSouth Africa

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