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Table 1 Baseline characteristics of the study patients

From: Tight computerized versus conventional glucose control in the ICU: a randomized controlled trial

Characteristics TGC (n = 1,336) GGC (n = 1,312)
Age, year; mean (SD) 61 (16) 62 (16)
Male sex, n (%) 862 (64.5) 844 (64.3)
Weight, kg; mean (SD), [n] 80 (20) [1,278] 78 (20) [1,271]
Body mass indexa, mean (SD), [n] 26.9 (6.8) [1,251] 26.8 (6.0) [1,243]
  <18.5, n (%) 48/1,251 (3.8) 34/1,243 (2.7)
  18.5–30, n (%) 930/1,251 (74.3) 928/1,243 (74.7)
  >30, n (%) 273/1,251 (21.8) 281/1,243 (22.6)
SAPS II scoreb, mean (SD), [n] 51 (19) [1,334] 51 (19) [1,309]
  SAPS II >50, n (%) 633/1,334 (47.5) 617/1,209 (47.1)
McCabe score, mean (SD) 1.4 (0.6) 1.5 (0.6)
Reason for ICU admission
  Surgical (emergency), n (%) 417 (31.2) 380 (29.0)
  Surgical (scheduled), n (%) 121 (9.1) 141 (10.7)
  Nonsurgical, n (%) 798 (59.7) 791 (60.3)
Polytrauma patients, n (%) 91 (6.8) 85 (6.5)
Location before admission
  Emergency department, n (%) 589 (44.1) 539 (41.1)
  Hospital floor (or ward), n (%) 370 (27.7) 398 (30.3)
  Another ICU, n (%) 153 (11.5) 135 (10.3)
  Intermediate care unit, n (%) 189 (14.2) 212 (16.2)
  Extended care facility center, n (%) 35 (2.6) 28 (2.1)
History of diabetes mellitus, n (%) 262/1,335 (19.6) 274 (20.9)
  Type 1 diabetes, n (%) 42/1,335 (3.1) 43 (3.3)
  Type 2 diabetes, n (%) 220/1,335 (16.5) 231 (17.6)
  Previous treatment with insulinc, n (%) 71/262 (27.1) 64/274 (23.4)
  Previous treatment with antidiabetic drugsd, n (%) 71/220 (32.3) 69/231 (29.9)
Category of main diagnosise
  Respiratory, n (%) 346 (25.9) 310 (23.6)
  Cardiovascular, n (%) 170 (12.7) 201 (15.3)
  Gastrointestinal or liver, n (%) 41 (3.1) 59 (4.5)
  Renal, n (%) 28 (2.1) 20 (1.5)
  Neurologic, n (%) 188 (14.1) 198 (15.1)
  Hematologic or oncologic, n (%) 9 (0.7) 7 (0.5)
  Metabolic, n (%) 10 (0.7) 7 (0.5)
  Other medical category, n (%) 44 (3.3) 43 (3.3)
  Gastrointestinal or urological surgery, n (%) 182 (13.6) 187 (14.3)
  Cardiac surgery, n (%) 111 (8.3) 91 (6.9)
  Vascular surgery, n (%) 41 (3.1) 35 (2.7)
  Neurosurgery, n (%) 76 (5.7) 76 (5.8)
  Orthopedic surgery, n (%) 29 (2.2) 28 (2.1)
  Thoracic surgery, n (%) 36 (2.7) 34 (2.6)
  Other surgical category, n (%) 25 (1.9) 15 (1.1)
Blood glucose level, mmol/L; mean (SD), [n] 9.4 (4.6) [1,292] 9.1 (4.2) [1,271]
Blood glucose level >10.0 mmol/L, n (%) 400/1,292 (31.0) 386/1,271 (30.4)
Plasma creatinine, μmol/L; mean (SD), [n] 142 (138) [1,333] 142 (140) [1,308]
Plasma urea, mmol/L; mean (SD), [n] 11.2 (9.7) [1,330] 10.9 (8.9) [1,307]
  1. Data are presented as the number, with the percentage in parenthesis unless other specified. Each statistic was computed on the non-missing value, i.e., the whole sample unless specifically indicated. International System of Units (SI) conversion factors: to convert blood glucose levels from mmol/L to mg/dL, multiply by 18.01
  2. TGC Tight computerized glucose control, CGC conventional non-computerized glucose control, SAPS simplified acute physiology score, ICU intensive care unit
  3. aThe body mass index is the weight in kilograms divided by the square of the height in meters
  4. bSimplified Acute Physiology Score (SAPS II) scores can range from 0 to 156. with higher scores indicating more severe illness [30]
  5. cPercentages of patients with previous treatment with insulin were calculated only for patients with an history of diabetes mellitus
  6. dPercentages of patients with previous treatment with antidiabetic drugs were calculated only for patients with type 2 diabetes
  7. eCategory of main diagnosis is known in 1,311 of the 1,312 patients of the CGC group