The concentrations and distributions of five sulfonamide, three tetracycline, and two macrolide antibiotics in leachates from three landfill sites in northern Zhejiang Province, China, were determined by solid-phase extraction and ultra-high performance liquid chromatography mass spectrometry. Most of the antibiotics were detected in the leachate samples. The concentrations and distributions of the antibiotics in leachates of different ages were very different. The total sulfonamide, tetracycline, and macrolide concentrations in the leachates ranged from not detected to 1.57 × 103, not detected to 5.19 × 103, and 7.30 to 5.42 × 102 ng/L, respectively. The total concentrations of detectable antibiotics were higher in fresh leachates than aged and middle-aged leachates. Higher TC-group concentrations were found in the leachates than have been found in previously published studies of landfill leachates in China. The results improve our understanding of and ability to manage antibiotic residues in landfills.
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Chen K, Zhou JL (2014) Occurrence and behavior of antibiotics in water and sediments from the Huangpu River, Shanghai, China. Chemosphere 95:604–612
Gothwal R, Shashidhar T (2014) Antibiotic pollution in the environment: a review. Clean: Soil, Air, Water 43:479–489
Ho YB, Zakaria MP, Latif PA, Saari N (2014) Occurrence of veterinary antibiotics and progesterone in broiler manure and agricultural soil in Malaysia. Sci Total Environ 488–489:261–267
Hu XG, Zhou QX, Luo Y (2010) Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, northern China. Environ Pollut 158:2992–2998
Li YW, Wu XL, Mo CH, Yai YP, Huang XP, Xiang L (2011) Investigation of sulfonamide, tetracycline, and quinolone antibiotics in vegetable farmland soil in the Pearl River Delta area, southern China. J Agric Food Chem 59:7268–7276
Li W, Shi Y, Gao L, Liu J, Cai Y (2013) Occurrence and removal of antibiotics in a municipal wastewater reclamation plant in Beijing, China. Chemosphere 92:435–444
Topal M, Topal EIA (2016) Determination and monitoring of tetracycline and degradation products in landfill leachate. Clean: Soil, Air, Water 44:444–450
Venglovsky J, Sasakova N, Placha I (2009) Pathogens and antibiotic residues in animal manures and hygienic and ecological risks related to subsequent land application. Bioresource Technol 100:5386–5391
Wang H, Chu YX, Fang CR (2017) Occurrence of veterinary antibiotics in swine manure from large-scale feedlots in Zhejiang province, China. Bull Environ Contam Toxicol 98:472–477
Wu D, Huang ZT, Yang K, Graham D, Xie B (2015) Relationships between antibiotics and antibiotic resistance gene levels in municipal solid waste leachates in Shanghai, China. Environ Sci Technol 49:4122–4128
Wu D, Huang XH, Sun JZ, Graham DW, Xie B (2017) Antibiotic resistance genes and associated microbial community conditions in aging landfill systems. Environ Sci Technol 51:12859–12867
Xi H, Sun JZ, Xie B (2018) The study of characteristics of antibiotic residues in municipal solid waste landfill. Acta Scien Circum 38:300–309 (in Chinese)
Yi XZ, Tran NH, Yin TR, He YL, Gin KYH (2017) Removal of selected PPCPs, EDCs and antibiotic resistance genes in landfill leachate by a full-scale constructed wetlands system. Water Res 121:46–60
Yu ZF, He PJ, Shao LM, Zhang H, Lu F (2016) Co-occurrence of mobile genetic elements and antibiotic resistance genes in municipal solid waste landfill leachates: a preliminary insight into the role of landfill age. Water Res 106:583–592
Zhang QQ, Ying GG, Pan CG, Liu YS, Zhao JL (2015) Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling and linkage to bacterial resistance. Environ Sci Technol 49:6772–6782
Zhao L, Dong YH, Wang H (2010) Residues of veterinary antibiotics in manures from feedlot livestock in eight provinces of China. Sci Total Environ 408:1069–1075
Zhou LJ, Ying GG, Zhang RQ, Liu S, Lai HJ, Chen ZF, Yang B, Zhao JL (2013) Use patterns, excretion masses and contamination profiles of antibiotics in a typical swine farm, south China. Environ Sci Proc Impacts 15:802–813
This work was funded by the National Natural Science Foundation of China (Grant Nos. 51678531, 51878617, and 51708505). We thank Gareth Thomas, PhD, from Liwen Bianji, Edanz Group China (www.liwenbianji.cn/ac), for editing the English text of a draft of this manuscript.
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Fang, C., Chen, B., Zhuang, H. et al. Antibiotics in Leachates from Landfills in Northern Zhejiang Province, China. Bull Environ Contam Toxicol 105, 36–40 (2020). https://doi.org/10.1007/s00128-020-02894-x