Table 1 Joinpoint analysis of time trends in age-standardised all-cause and cause-specific mortality rates in men and women with diabetes in Hong Kong between 2001 and 2016

From: Secular trends in all-cause and cause-specific mortality rates in people with diabetes in Hong Kong, 2001–2016: a retrospective cohort study

Cause of deathMortality rate (per 10,000 person-years)Time period 1Time period 2Time period 3
 20012016AAPC (95% CI)YearAPC (95% CI)YearAPC (95% CI)YearAPC (95% CI)
Men
  All-cause         
    All ages325.1154.9−5.1 (−5.7, −4.6)*2001–2006−9.4 (−11.1, −7.8)*2006–2016−2.9 (−3.4, −2.4)*  
    20–44 years76.650.7−3.2 (−7.3, 1.0)2001–2008−10.1 (−16.2, −3.5)*2008–20163.2 (−3.4, 10.2)  
    45–59 years199.787.9−5.4 (−7.1, −3.6)*2001–2005−12.6 (−18.6, −6.2)*2005–2016−2.6 (−3.7, −1.4)*  
    60–74 years497.5195.0−6.4 (−7.4, −5.4)*2001–2006−11.1 (−13.8, −8.2)*2006–2016−3.9 (−4.8, −3.1)*  
     ≥75 years1602.3808.0−4.7 (−5.3, −4.0)*2001–2006−7.6 (−9.5, −5.8)*2006–2016−3.1 (−3.6, −2.7)*  
  CVD         
    All ages89.124.8−8.5 (−9.5, −7.4)*2001–2004−17.7 (−22.4, −12.7)*2004–2016−6.0 (−6.7, −5.3)*  
    45–59 years47.019.2−6.4 (−10.2, −2.4)*2001–2005−20.4 (−28.4, −11.5)*2005–20096.1 (−7.5, 21.8)2009–2016−4.4 (−7.6, −1.1)*
    60–74 years136.831.7−9.9 (−12.0, −7.7)*2001–2004−18.3 (−27.6, −7.8)*2004–2016−7.6 (−8.9, −6.4)*  
     ≥75 years491.8110.3−9.2 (−10.0, −8.4)*2001–2016−9.2 (−10.0, −8.4)*    
  Cancer         
    All ages80.027.9−7.0 (−7.8, −6.1)*2001–2016−7.0 (−7.8, −6.1)*    
    45–59 years69.818.6−7.4 (−8.7, −6.1)*2001–2016−7.4 (−8.7, −6.1)*    
    60–74 years163.854.3−6.9 (−8.0, −5.9)*2001–2016−6.9 (−8.0, −5.9)*    
     ≥75 years299.0118.5−6.0 (−6.7, −5.3)*2001–2016−6.0 (−6.7, −5.3)*    
  Pneumonia         
    All ages44.335.3−3.0 (−7.6, 1.8)2001–2006−8.5 (−18.0, 2.0)2006–20109.1 (−5.5, 26.0)  
    45–59 years8.28.90.3 (−2.1, 2.7)2001–20160.3 (−2.1, 2.7)    
    60–74 years52.733.7−3.6 (−7.8, 0.7)2001–2006−10.5 (−17.8, −2.6)*2006–20108.1 (−7.0, 25.7)2010–2016−5.1 (−8.8, −1.2)*
     ≥75 years322.0276.8−1.4 (−3.0, 0.3)2001–2016−1.4 (−3.0, 0.3)    
Women
  All-cause         
    All ages212.598.8−5.5 (−7.2, −3.7)*2001–2006−9.7 (−14.2, −5.0)*2006–2016−3.3 (−5.1, −1.5)*  
    20–44 years36.033.5−1.2 (−6.5, 4.4)2001–2016−1.2 (−6.5, 4.4)    
    45–59 years97.144.5−5.3 (−7.5, −3.1)*2001–2006−11.2 (−16.9, −5.0)*2006–2016−2.3 (−4.2, −0.3)*  
    60–74 years319.2101.2−7.6 (−8.7, −6.5)*2001–2006−14.3 (−17.1, −11.3)*2006–2016−4.1 (−5.2, −3.1)*  
     ≥75 years1246.3594.9−4.7 (−5.9, −3.6)*2001–2006−8.1 (−11.3, −4.7)*2006–2016−3.0 (−3.9, −2.2)*  
  CVD         
    All ages65.814.1−9.8 (−11.4, −8.2)*2001–2004−16.2 (−23.3, −8.4)*2004–2016−8.2 (−9.2, −7.1)*  
    45–59 years14.25.9−6.2 (−8.6, −3.8)*2001–2016−6.2 (−8.6, −3.8)*    
    60–74 years96.415.0−12.5 (−15.1, −9.9)*2001–2004−25.7 (−33.3, −17.3)*2004–2009−5.7 (−12.1, 1.2)2009–2016−11.1 (−13.8, −8.3)*
     ≥75 years471.1105.1−9.0 (−9.8, −8.2)*2001–2016−9.0 (−9.8, −8.2)*    
  Cancer         
    All ages45.818.5−6.1 (−7.1, −5.0)*2001–2006−10.6 (−13.4, −7.8)*2006–2016−3.7 (−4.8, −2.6)*  
    45–59 years35.614.9−5.6 (−7.0, −4.1)*2001–2016−5.6 (−7.0, −4.1)*    
    60–74 years101.234.0−7.7 (−10.1, −5.2)*2001–2005−17.5 (−25.4, −8.8)*2005–2016−3.8 (−5.7, −1.9)*  
     ≥75 years169.075.7−5.3 (−6.1, −4.5)*2001–2016−5.3 (−6.1, −4.5)*    
  Pneumonia         
    All ages30.826.0−2.4 (−5.6, 0.9)2001–2005−12.0 (−18.6, −4.8)*2005–20098.7 (−1.2, 19.6)2009–2016−2.7 (−7.2, 2.1)
    45–59 years4.55.81.6 (−0.6, 3.7)2001–20161.6 (−0.6, 3.7)    
    60–74 years21.214.3−1.5 (−3.9, 1.1)2001–2016−1.5 (−3.9, 1.1)    
     ≥75 years260.0171.4−1.1 (−2.6, 0.3)2001–2016−1.1 (−2.6, 0.3)    
  1. Joinpoint regression analysis for cause-specific mortality rates was only performed for age subgroups of 45 years and older
  2. *p< 0.05