Skip to main content

Advertisement

SpringerLink
Log in

Das Nierenzellkarzinom beim Kind

Eine seltene Differenzialdiagnose zum Wilms-Tumor

Pediatric renal cell carcinoma

A rare differential diagnosis of Wilms’ tumor

  • Kasuistiken
  • Published:
Der Urologe Aims and scope Submit manuscript

Zusammenfassung

Das papilläre Nierenzellkarzinom beim Kind ist eine seltene Erkrankung und sollte als eigenständige Entität betrachtet werden, da sie sich hinsichtlich Symptomatik, Verlauf und Prognose vom Erwachsenentyp unterscheidet. Es wird die klinische und diagnostische Problematik bei Diagnosestellung, Prognose und Therapie dieser im jugendlichen Alter sehr seltenen Erkrankung anhand der Literatur diskutiert.

Abstract

Renal cell carcinoma (RCC) is a very rare pediatric disease and should be treated as an entity of its own because of differences in symptoms, therapy, and prognosis from the adult form of the disease. Our objective is to discuss the difficulties in clinical diagnosis, prognosis, and therapy of this very rare disease in children and to provide a review of the current literature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abb. 1
Abb. 2

Literatur

  1. Al-Saleem T, Wessner Ll, Scheithauer BW et al. (1998) Malignant tumors of the kidney, brain, and soft tissues in children and young adults with the tuberous sclerosis complex. Cancer 83: 2208–2216

    Article  PubMed  CAS  Google Scholar 

  2. Beland MD, Mayo-Smith WW, Dupuy DE et al. (2007) Diagnostic yield of 58 consecutive imaging-guided biopsies of solid renal masses: should we biopsy all that are indeterminate? Am J Roentgenol 188: 792–797

    Article  Google Scholar 

  3. Carcao MD, Taylor GP, Greenberg Ml et al. (1998) Renal-cell carcinoma in children: a different disorder from its adult counterpart? Med Pediatr Oncol 31: 153–158

    Article  PubMed  CAS  Google Scholar 

  4. Charles AK, Vujanic GM, Berry PJ (1998) Renal tumours of childhood. Histopathology 32: 293–309

    Article  PubMed  CAS  Google Scholar 

  5. Escudier B (2006) Metastatic renal cell carcinoma and its treatments. Ann Urol (Paris) 40(Suppl 3): 82–85

    Google Scholar 

  6. Estrada CR, Suthar AM, Eaton S et al. (2005) Renal cell carcinoma: Children’s Hospital Boston experience. Urology 66: 1296–1300

    Article  PubMed  Google Scholar 

  7. Garcia JA, Rini BI (2007) Recent progress in the management of advanced renal cell carcinoma. CA Cancer J Clin 57: 112–125

    Article  PubMed  Google Scholar 

  8. Geller JI, Dome JS (2004) Local lymph node involvement does not predict poor outcome in pediatric renal cell carcinoma. Cancer 101:1575–1583

    Article  PubMed  Google Scholar 

  9. Hartman DS, Davis CJ Jr, Madewell JE et al. (1982) Primary malignant renal tumors in the second decade of life: Wilms tumor versus renal cell carcinoma. J Urol 127: 888–891

    PubMed  CAS  Google Scholar 

  10. Indolfi P, Terenziani M, Casale F et al. (2003) Renal cell carcinoma in children: a clinicopathologic study. J Clin Oncol 21:530–535

    Article  PubMed  Google Scholar 

  11. Ljungberg B, Hanbury B, Kuscyk MA et al. (2007) Guidelines On Renal Cell Carcinoma. Eur Urol 51(6): 1502–1510

    Article  PubMed  Google Scholar 

  12. Lowe LH, Isuani BH, Heller RM et al. (2000) Pediatric renal masses: Wilms tumor and beyond. Radiographics 20: 1585–1603

    PubMed  CAS  Google Scholar 

  13. Mchugh K (2007) Renal and adrenal tumours in children. Cancer Imag 7: 41–51

    Article  Google Scholar 

  14. Medeiros LJ, Palmedo G, Krigman HR et al. (1999) Oncocytoid renal cell carcinoma after neuroblastoma: a report of four cases of a distinct clinicopathologic entity. Am J Surg Pathol 23: 772–780

    Article  PubMed  CAS  Google Scholar 

  15. Nelson JB, Oyasu R, Dalton DP (1994) The clinical and pathological manifestations of renal tumors in von Hippel-Lindau disease. J Urol 152: 2221–2226

    PubMed  CAS  Google Scholar 

  16. Pastore G, Znaor A, Spreafico F et al. (2006) Malignant renal tumours incidence and survival in European children (1978–1997): report from the Automated Childhood Cancer Information System project. Eur J Cancer 42: 2103–2114

    Article  PubMed  Google Scholar 

  17. Rathmell WK, Martz CA, Rini BI (2007) Renal cell carcinoma. Curr Opin Oncol 19: 234–240

    Article  PubMed  Google Scholar 

  18. Renshaw AA, Granter SR, Fletcher JA et al. (1999) Renal cell carcinomas in children and young adults: increased incidence of papillary architecture and unique subtypes. Am J Surg Pathol 23: 795–802

    Article  PubMed  CAS  Google Scholar 

  19. Selle B, Furtwangler R, Graf N et al. (2006) Population-based study of renal cell carcinoma in children in Germany, 1980–2005: more frequently localized tumors and underlying disorders compared with adult counterparts. Cancer 107: 2906–2914

    Article  PubMed  Google Scholar 

  20. Teratani T, Domoto T, Kuriki K et al. (2007) Detection of transcript for brain-type fatty Acid-binding protein in tumor and urine of patients with renal cell carcinoma. Urology 69: 236–240

    Article  PubMed  Google Scholar 

  21. Vujanic GM, Kelsey A, Mitchell C et al. (2003) The role of biopsy in the diagnosis of renal tumors of childhood: Results of the UKCCSG Wilms tumor study 3. Med Pediatr Oncol 40: 18–22

    Article  PubMed  Google Scholar 

Download references

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

  1. Klinik und Poliklinik für Urologie, Universitätsklinikum Bonn, Sigmund-Freud-Straße 25, 53105, Bonn, Deutschland

    N. Fischer, P.J. Bastian, J. Ellinger & S.C. Müller

  2. Pädiatrische Hämatologie und Onkologie, Universitätsklinikum, Bonn, Deutschland

    A. Simon & U. Bode

  3. Institut für Pathologie, Universitätsklinikum, Bonn, Deutschland

    K. Biermann

  4. Radiologische Universitätsklinik, Universitätsklinikum, Bonn, Deutschland

    D. Hadizadeh

Authors
  1. N. Fischer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P.J. Bastian
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Ellinger
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Simon
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. U. Bode
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. K. Biermann
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. D. Hadizadeh
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. S.C. Müller
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to N. Fischer.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fischer, N., Bastian, P., Ellinger, J. et al. Das Nierenzellkarzinom beim Kind. Urologe 47, 620–623 (2008). https://doi.org/10.1007/s00120-007-1620-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00120-007-1620-2

Schlüsselwörter

Keywords

Search

Navigation