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Herpes genitalis

Genital herpes

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Zusammenfassung

Beim Herpes genitalis handelt es sich um eine ulzerative, nicht heilbare, rezidivierende Geschlechtskrankheit von weltweit zunehmender epidemiologischer Bedeutung. Erreger ist das Herpes-simplex-Virus (HSV-1 und HSV-2). Die Übertragung erfolgt durch engen Schleimhautkontakt, zumeist während asymptomatischer Virusausscheidung. Das Virus persistiert im Spinalganglion, wo es sich dem Immunsystem entzieht. Den wichtigsten Risikofaktor stellen häufige Partnerwechsel dar. Nach einer schwerer verlaufenden Erstinfektion kommt es zu milderen Rezidiven in unterschiedlicher Häufigkeit. Die Diagnose wird klinisch, mikrobiologisch und serologisch gestellt. Therapeutisch stehen diverse Virostatika zur Verfügung.

Abstract

Genital herpes simplex virus (HSV-1 and HSV-2) infection is an ulcerative, lifelong, recurring sexually transmitted disease of increasing epidemiologic worldwide importance. Transmission occurs by close skin contact, usually during asymptomatic virus shedding. The virus persists in the dorsal root ganglion where it is not accessible to the host’s immune system. The most important risk factor is a person’s number of lifetime sex partners. The more extensive first-episode infection is followed by milder recurrences. Recurrence rates differ greatly. The diagnosis is made clinically, microbiologically, and serologically. There are several virostatic agents available for treatment.

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Authors and Affiliations

  1. Urologische Klinik und Poliklinik, Klinikum der Ludwig-Maximilians-Universität, Marchioninistraße 15, 81377, München, Deutschland

    C. J. Adam, M. Staehler, W. Khoder & C. Stief

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  1. C. J. Adam
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  2. M. Staehler
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  3. W. Khoder
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  4. C. Stief
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Correspondence to C. J. Adam.

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Adam, C.J., Staehler, M., Khoder, W. et al. Herpes genitalis. Urologe 45, 1509–1513 (2006). https://doi.org/10.1007/s00120-006-1231-3

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  • DOI: https://doi.org/10.1007/s00120-006-1231-3

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