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Immunonutrition nach Trauma

Immunonutrition after trauma

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Zusammenfassung

Immunonutrition kann gegenüber herkömmlicher klinischer Ernährung das klinische Outcome verbessern. Nach schwerem Trauma vermindert eine enterale immunmodulierende Sondenkost, welche mit Arginin, Omega-3-Fettsäuren und Nukleotiden angereichert ist, die Rate an posttraumatischen Infektionen. Bei akutem Lungenversagen konnte eine kontinuierlich verabreichte enterale Sondenkost, die hochdosiert Omega-3-Fettsäuren, Gamma-Linolensäure und Antioxidantien enthält, die Mortalität reduzieren. Glutamin sollte enteral oder bei Indikation einer parenteralen Ernährungstherapie, hochdosiert i. v. zugeführt werden.

Abstract

Immunonutrition may be superior to standard clinical nutrition in specific clinical situations. After severe trauma, an enteral immuno-enhancing diet, enriched with arginine, omega-3 fatty acids, and nucleotides, decreases infectious complications. During acute respiratory distress syndrome, a continuous enteral diet with high-dose omega-3 fatty acids, gamma-linolenic acid, and antioxidants improved clinical outcome. Glutamine should be administered enterally or parenterally whenever total parenteral nutrition is indicated.

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Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehungen hin: TF erhält Vortragshonorare von Abbott, B Braun, Baxter, Fresenius.

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  1. Klinik für Anästhesiologie, Operative Intensivmedizin und Schmerztherapie, Klinikum Neuperlach, Städtisches Klinikum München GmbH, Oskar-Maria-Graf-Ring 51, 81737, München, Deutschland

    T.W. Felbinger, M. Sachs & H.P. Richter

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  1. T.W. Felbinger
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  2. M. Sachs
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  3. H.P. Richter
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Correspondence to T.W. Felbinger.

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Felbinger, T., Sachs, M. & Richter, H. Immunonutrition nach Trauma. Unfallchirurg 114, 981–986 (2011). https://doi.org/10.1007/s00113-011-2033-7

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