Nichtinvasive bildgebende Diagnostik bei Hauterkrankungen im Kindesalter

Noninvasive diagnostic imaging in pediatric skin lesions

Zusammenfassung

Die optische Kohärenztomographie (OCT) und die konfokale Lasermikroskopie (KLM) ermöglichen eine nichtinvasive bildgebende Diagnostik der Haut. Gerade weil bei Kindern die Indikation für eine Hautbiopsie eher zurückhaltend gestellt wird, können OCT und KLM für die Abklärung von kindlichen Hautveränderungen hilfreich sein. Außerdem stellen Biopsien immer nur eine Momentaufnahme eines kleinen Bezirkes der Haut dar, während die nichtinvasiven Methoden ermöglichen, mehrere Lokalisationen im Zeitverlauf zu untersuchen, sodass auch dynamische Veränderungen und Therapieverläufe sichtbar gemacht werden können. In der pädiatrischen Dermatologie eignen sie sich insbesondere zur Abklärung atypischer Pigmentläsionen, bei infektiösen Dermatosen wie Skabies oder Tinea und zur Diagnostik entzündlicher und degenerativer Dermatosen.

Abstract

Optical coherence tomography (OCT) and reflectance confocal laser microscopy (RCM) allow noninvasive imaging diagnostics of the skin. Since the indication for a biopsy in children is generally made cautiously, OCT and KLM can be helpful in the clarification of pediatric skin lesions. In addition, biopsies only represent a snapshot of a small area of the skin, while noninvasive methods allow several locations to be examined over time, so that dynamic changes and the course of therapy can also be determined. In pediatric dermatology, these diagnostic methods are particularly suitable for the clarification of atypical pigment lesions, for infectious dermatoses such as scabies or tinea, and for the diagnosis of inflammatory and degenerative dermatoses.

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Correspondence to Dr. S. Schuh.

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Interessenkonflikt

S. Schuh, A.B. Weins und J. Welzel geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Schuh, S., Weins, A.B. & Welzel, J. Nichtinvasive bildgebende Diagnostik bei Hauterkrankungen im Kindesalter. Hautarzt (2021). https://doi.org/10.1007/s00105-020-04753-6

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Schlüsselwörter

  • Optische Kohärenztomographie
  • Konfokale Lasermikroskopie
  • Optische Biopsie
  • Pädiatrische Dermatologie
  • Therapiemonitoring

Keywords

  • Optical coherence tomography
  • Reflectance confocal laser microscopy
  • Optical biopsy
  • Pediatric dermatology
  • Treatment monitoring