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Durvalumab nach einer Radiochemotherapie ist beim NSCLC im Stadium III derzeit die vielversprechendste Therapie

Durvalumab after chemoradiotherapy is currently the most promising treatment for stage III NSCLC

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Literatur

  1. Yoon SM, Shaikh T, Hallman M (2017) Therapeutic management options for stage IIInon-small cell lung cancer. World J Clin Oncol 8:1–20

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Deng L, Liang H, Burnette B et al (2014) Irradiation and anti-PD-L1 treatment synergisticallypromote antitumor immunity in mice. J Clin Invest 124:687–695

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Antonia SJ, Villegas A, Daniel D et al (2017) Durvalumab after chemoradiotherapy instage III non-small-cell lung cancer. N Engl J Med 377:1919–1929

    Article  CAS  PubMed  Google Scholar 

  4. Antonia SJ, Villegas A, Daniel D et al (2018) PACIFIC investigators. Overall survival with durvalumab after chemoradiotherapy in stage III NSCLC. N Engl J Med 379:2342–2350

    Article  CAS  PubMed  Google Scholar 

  5. Bradley JD, Paulus R, Komaki R et al (2015) Standard-dose versus high-dose conformal radiotherapy with concurrent and consoli-dation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study. Lancet Oncol 16:187–199

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Butts C, Socinski MA, Mitchell PL et al (2014) Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): a randomised, double-blind, phase 3 trial. Lancet Oncol 15:59–68

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Martin Wilhelm.

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Antonia SJ, Villegas A, Daniel D, et al.; PACIFIC Investigators (2018) Overall survival with durvalumab after chemoradiotherapy in stage III NSCLC. N Engl J Med 379:2342–50

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Wilhelm, M. Durvalumab nach einer Radiochemotherapie ist beim NSCLC im Stadium III derzeit die vielversprechendste Therapie. Strahlenther Onkol 195, 691–692 (2019). https://doi.org/10.1007/s00066-019-01456-3

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  • DOI: https://doi.org/10.1007/s00066-019-01456-3

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