Skip to main content
Log in

Late Toxicity in Children Undergoing Hematopoietic Stem Cell Transplantation with TBI-containing Conditioning Regimens for Hematological Malignancies

  • Supplement Article
  • Published:
Strahlentherapie und Onkologie Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Belkacemi Y, Labopin M, Vernant JP, et al. Cataracts after total body irradiation and bone marrow transplantation in patients with acute leukaemia in complete remission: a study of the European Group For Blood and Marrow Transplantation. Int J Radiat Oncol Biol Phys 1998;41:459–468.

    Article  Google Scholar 

  2. Berger C, Le-Gallo B, Donadieu J, Richard O, Devergie A, Galambrun C, et al. Late thyroid toxicity in 153 long-term survivors of allogeneic bone marrow transplantation for acute lymphoblastic leukaemia. Bone Marrow Transplant 2005;35:991–995.

    Article  PubMed  CAS  Google Scholar 

  3. Bölling T, Könemann S, Ernst I, Willich N. Late effects of radiotherapy to the thorax in children: a review of the literature. Strahlenther Onkol 2008;184:289–295.

    Article  PubMed  Google Scholar 

  4. Chou RH, Garrett BW, Kramer JH, Wara DW, Matthay KK, Crittenden MR, Swift PS, Cowan MJ, Wara WM. Toxicities of Total Body Irradiation for pediatric bone marrow transplantation. Int J Rad Oncol Biol Phys 1996;34:843–851.

    CAS  Google Scholar 

  5. Cohen A, Rovelli A, Bakker B et al. Final height of patients who underwent bone marrow transplantation for haematological disorders during childhood: a study by the Working Party for Late Effects- EHSCT. Blood 1999;93:4109–4115.

    PubMed  CAS  Google Scholar 

  6. Dörr W, Herrmann T. Second Tumors after Oncologic Treatment. Strahlenther Onkol 2008;184:67–72.

    Article  PubMed  Google Scholar 

  7. Faraci M, Barra S, Cohen A, Lanino E, Grisolia F, Miano M, et al. Very late nonfatal consequences of fractionated TBI in children undergoing bone marrow transplant. Int J Radiat Oncol Biol Phys 2005;63:1568–1575.

    Article  PubMed  Google Scholar 

  8. Ferry C, Gemayel G, Rocha V, et al. Long-term outcomes after allogeneic stem cells transplantation for children with haematological malignancies. Bone Marrow Transplant 2007;40:219–224.

    Article  PubMed  CAS  Google Scholar 

  9. Hoffmeister PA, Madtes DK, Storer BE, Sandres JE. Pulmonary function in long-term survivors of pediatric hematopoietic cell transplantation. Pediatr Blood Cancer 2006;47:594–606.

    Article  PubMed  Google Scholar 

  10. Kolb HJ, Socié G, Duell T, Van Lint MT, Tichelli A, Apperley JF, et al. Malignant neoplasms in long-term survivors of bone marrow transplantation. Late Effects Working Party of the European Cooperative Group for Blood and Marrow Transplantation and the European Late Effect Project Group. Ann Intern Med 1999;131:738–744.

    PubMed  CAS  Google Scholar 

  11. Ljungman P, Urbano-Ispizua A, Cavazzana-Calvo M, Demirer T, Dini G, Einsele H, Gratwohl A, Madrigal A, Niederwieser D, Passweg J, Rocha V, Saccardi R, Schouten H, Schmitz N, Socie G, Sureda A, Apperley J, European Group for Blood and Marrow. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe. Bone Marrow Transplant 2006;37:439–449.

    Article  PubMed  CAS  Google Scholar 

  12. Mertens AC, Ramsay NK, Kouris S, Neglia JP. Patterns of gonadal dysfunction following bone marrow transplantation. Bone Marrow Transplant 1998;22:345–350.

    Article  PubMed  CAS  Google Scholar 

  13. Ramm U, Licher J, Moog J, Scherf C, Kara E, Böttcher HD, Rödel C, Mose S. In vivo dosimetry with semiconducting diodes for dose verification in total-body irradiation. A 10-year experience. Strahlenther Onkol 2008;184:376–380.

    Article  PubMed  Google Scholar 

  14. Rizzo JD, Wingard JR, Tichelli A, Lee SJ, Van Lint MT, Burns LJ, et al. Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation: joint recommendations of the European Group for Blood and Marrow Transplantation, Center for International Blood and Marrow Transplant Research, and the American Society for Blood and Marrow Transplantation (EHSCT/CIHSCTR/ASHSCT). Bone Marrow Transplant 2006;37:249–261.

    Article  PubMed  CAS  Google Scholar 

  15. Schneider RA, Schultze J, Jensen JM, Hebbinghaus D, Galalae R, Kimmig BN. 20 years of experience in static intensity-modulated total-body irradiation and lung toxicity. Results in 257 consecutive patients. Strahlenther Onkol 2007;183:545–551.

    Article  PubMed  Google Scholar 

  16. Shalitin S, Phillip M, Stein J, Goshen Y, Carmi D, Yaniv I. Endocrine dysfunction and parameters of the metabolic syndrome after bone marrow transplantation during childhood and adolescence. Bone Marrow Transplant 2006;37:1109–1117.

    Article  PubMed  CAS  Google Scholar 

  17. Shank B, Hoppe RT. Radiotherapeutic principles of hematopoietic cell transplantation. In: Blume KG, Forman SJ, Appelbaum FR, eds. Thomas Hematopoietic Cell Transplantation, 3rd ed., Blackwell Publishing Ltd: Malden, MA, 2004:178–197.

    Google Scholar 

  18. Socié G, Curtis RE, Deeg HJ, Sobocinski KA, Filipovich AH, Travis LB, et al. New malignant diseases after allogeneic marrow transplantation for childhood acute leukemia. J Clin Oncol 2000;18:348–357.

    PubMed  Google Scholar 

  19. Storb R. History of pediatric stem cell transplantation. Pediatr Transplant 2004;8(Suppl 5):5–11.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Umberto Ricardi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ricardi, U., Filippi, A.R., Biasin, E. et al. Late Toxicity in Children Undergoing Hematopoietic Stem Cell Transplantation with TBI-containing Conditioning Regimens for Hematological Malignancies. Strahlenther Onkol 185 (Suppl 2), 17–20 (2009). https://doi.org/10.1007/s00066-009-1008-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00066-009-1008-x

Key Words:

Navigation