MRI Findings of Adult-Onset Orbital Xanthogranulomatous Disease

A Case Report
  • Joo Kyung Sim
  • Ji Ye Lee
  • Sun Young Jang
  • Susie Chin


Compliance with ethical guidelines

Conflict of interest

J.K. Sim, J.Y. Lee, S.Y. Jang and S. Chin declare that they have no competing interests.

Ethical standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from the individual participant included in the study.


  1. 1.
    Jakobiec FA, Mills MD, Hidayat AA, Dallow RL, Townsend DJ, Brinker EA, Charles NC. Periocular xanthogranulomas associated with severe adult-onset asthma. Trans Am Ophthalmol Soc. 1993;91:99-125; discussion 125–9.PubMedPubMedCentralGoogle Scholar
  2. 2.
    De Abreu MR, Chung CB, Biswal S, Haghighi P, Hesselink J, Resnick D. Erdheim-Chester disease: MR imaging, anatomic, and histopathologic correlation of orbital involvement. AJNR Am J Neuroradiol. 2004;25:627–30.PubMedGoogle Scholar
  3. 3.
    Miszkiel KA, Sohaib SA, Rose GE, Cree IA, Moseley IF. Radiological and clinicopathological features of orbital xanthogranuloma. Br J Ophthalmol. 2000;84:251–8.CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Rose GE, Patel BC, Garner A, Wright JE. Orbital xanthogranuloma in adults. Br J Ophthalmol. 1991;75:680–4.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Guo J, Wang J. Adult orbital xanthogranulomatous disease: review of the literature. Arch Pathol Lab Med. 2009;133:1994–7.PubMedGoogle Scholar
  6. 6.
    Sivak-Callcott JA, Rootman J, Rasmussen SL, Nugent RA, White VA, Paridaens D, Currie Z, Rose G, Clark B, McNab AA, Buffam FV, Neigel JM, Kazim M. Adult xanthogranulomatous disease of the orbit and ocular adnexa: new immunohistochemical findings and clinical review. Br J Ophthalmol. 2006;90:602–8.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Chu AC. The confusing state of the histiocytoses. Br J Dermatol. 2000;143:475–6.PubMedGoogle Scholar
  8. 8.
    Mazor RD, Manevich-Mazor M, Shoenfeld Y. Erdheim-Chester Disease: a comprehensive review of the literature. Orphanet J Rare Dis. 2013;8:137.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Hood MN, Ho VB, Smirniotopoulos JG, Szumowski J. Chemical shift: the artifact and clinical tool revisited. Radiographics. 1999;19:357–71.CrossRefPubMedGoogle Scholar
  10. 10.
    Herrick RC, Hayman LA, Taber KH, Diaz-Marchan PJ, Kuo MD. Artifacts and pitfalls in MR imaging of the orbit: a clinical review. Radiographics. 1997;17:707–24.CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of RadiologySoonchunhyang University Bucheon HospitalBucheonKorea (Republic of)
  2. 2.Department of OphthalmologySoonchunhyang University Bucheon HospitalBucheonKorea (Republic of)
  3. 3.Department of PathologySoonchunhyang University Bucheon HospitalBucheonKorea (Republic of)

Personalised recommendations