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Platypnea-orthodeoxia syndrome due to patent foramen ovale

An unusual cause of Cheyne–Stokes respiration

Platypnoe-Orthodeoxie-Syndrom bei persistierendem offenem Foramen ovale

Seltene Ursache einer Cheyne-Stokes-Atmung

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References

  1. Cheyne J (1818) A case of apoplexy in which the fleshy part of the heart is turned to fat. Dublin Hosp Rep 2:216–223

    Google Scholar 

  2. Stokes W (1854) The diseases of the heart and the aorta. Hodges and Smith, Dublin

  3. Berry R, Budhiraja R, Gottlieb D et al (2007) Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. J Clin Sleep Med 8:597–619

    Google Scholar 

  4. Oldenburg O, Lamp B, Faber L et al (2007) Sleep-disordered breathing in patients with symptomatic heart failure: a contemporary study of prevalence in and characteristics of 700 patients. Eur J Heart Fail 9:251–257

    Article  PubMed  Google Scholar 

  5. Schulz R, Blau A, Börgel J et al (2007) Sleep apnoea in heart failure. Eur Respir J 29:1201–1205

    Article  CAS  PubMed  Google Scholar 

  6. Bitter T, Prinz C, Faber L et al (2009) Sleep-disordered breathing in heart failure with normal left ventricular ejection fraction. Eur J Heart Fail 11:602–608

    Article  PubMed  Google Scholar 

  7. Javaheri S, Shukla R, Zeigler H, Wexler L (2007) Central sleep apnoea, right ventricular dysfunction, and low diastolic blood pressure are predictors of mortality in systolic heart failure. J Am Coll Cardiol 49:2028–2034

    Article  PubMed  Google Scholar 

  8. Bitter T, Westerheide N, Prinz C et al (2011) Cheyne—Stokes respiration and obstructive sleep apnoea are independent risk factors for malignant ventricular arrhythmias requiring appropriate cardioverter-defibrillator therapies in patients with congestive heart failure. Eur Heart J 32:61–74

    Article  PubMed  Google Scholar 

  9. Oldenburg O, Bitter T, Wiemer M et al (2009) Pulmonary capillary wedge pressure and pulmonary arterial pressure in heart failure patients with sleep-disordered breathing. Sleep Med 10:726–730

    Article  PubMed  Google Scholar 

  10. Yumino D, Redolfi S, Ruttanaumpawan P et al (2010) Nocturnal rostral fluid shift apnea in men with heart failure. Circulation 121(14):1598–1605

    Article  PubMed  Google Scholar 

  11. Solin P, Bergin P, Richardson M et al (1999) Influence of pulmonary capillary wedge pressure on central apnea in heart failure. Circulation 99:1574–1579

    Article  CAS  PubMed  Google Scholar 

  12. Arzt M, Harth M, Luchner A et al (2003) Enhanced ventilatory response to exercise in patients with chronic heart failure and central sleep apnea. Circulation 107:1998–2003

    Article  PubMed  Google Scholar 

  13. Javaheri S (1999) A mechanism of central sleep apnoea in patients with heart failure. N Engl J Med 341:949–954

    Article  CAS  PubMed  Google Scholar 

  14. Godart F, Rey C, Prat A et al (2000) Atrial right-to-left shunting causing severe hypoxemia despite normal right-sided pressures: report of 11 consecutive cases corrected by percutaneous closure. Eur Heart J 21:483–489

    Article  CAS  PubMed  Google Scholar 

  15. Sorrentino M, Resnekov L (1991) Patent foramen ovale associated with platypnea and orthodeoxia. Chest 100:1157–1158

    Article  CAS  PubMed  Google Scholar 

  16. Yumino D, Redolfi S, Ruttanaumpawan P et al (2010) Nocturnal rostral fluid shift: a unifying concept for the pathogenesis of obstructive and central sleep apnea in men with heart failure. Circulation 13:1598–1605

    Article  Google Scholar 

  17. Lorenzi-Filho G, Azevedo E, Parker J, Bradley T (2002) Relationship of PaCO2 to pulmonary wedge pressure in heart failure. Eur Respir J 19:37–40

    Article  CAS  PubMed  Google Scholar 

  18. Churchill E, Cope O (1929) The rapid shallow breathing resulting from pulmonary congestion and edema. J Exp Med 49:531–537

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  19. Kara T, Narkiewicz K, Somers VK (2003) Chemoreflexes—physiology and clinical implications. Acta Physiol Scand 177:377–384

    Article  CAS  PubMed  Google Scholar 

  20. Bloch K, Latshang T, Turk A et al (2010) Nocturnal periodic breathing during acclitimization at very high altitude at Mt. Muztagh Ata (7546 m). Am J Respir Crit Care Med 182:562–568

    Article  PubMed  Google Scholar 

  21. Han F, Subramanian S, Price ER et al (2002) Periodic breathing in the mouse. J Appl Physiol 92:1133–1140

    PubMed  Google Scholar 

  22. Andreas S, Mühlen F von zur, Stevens J, Kreuzer H (1998) Nocturnal oxygen and hypercapnicventilatory rsponse in patients with congestive heart failure. Respir Med 92:426–431

    Article  CAS  PubMed  Google Scholar 

  23. Kaye D, Lefkovits J, Jennings G et al (1995) Adverse consequences of high sympathetic nervous activation in the failing human heart. J Am Coll Cardiol 26:1257–1263

    Article  CAS  PubMed  Google Scholar 

  24. Efken C, Bitter T, Prib N et al (2013) Obstructive sleep apnoea: longer respiratory event lengths in patients with heart failure. Eur Respir J 41:1340–1346

    Article  PubMed  Google Scholar 

  25. Wedewardt J, Bitter T, Prinz C et al (2010) Cheyne-Stokes respiration in heart failure: cycle length is dependent on left ventricular ejection fraction. Sleep Med 11:137–142

    Article  PubMed  Google Scholar 

  26. Ulrich S, Fischler M, Speich R, Bloch KE (2008) Sleep-related breathing disorders in patients with pulmonary hypertension. Chest 133:1375–1380

    Article  CAS  PubMed  Google Scholar 

  27. Jilwan F, Escourrou P, Garcia G et al (2013) High occurrence of hypoxemic sleep respiratory disorders in precapillary pulmonary hypertension and mechanisms. Chest 143:47–55

    Article  PubMed  Google Scholar 

  28. Dumitrascu R, Tiede H, Eckermann J et al (2013) Sleep apnea in precapillary pulmonary hypertension. Sleep Med 14:247–251

    Article  PubMed  Google Scholar 

  29. Hoeper MM, Pletz MW, Golpon H, Welte T (2007) Prognostic value of blood gas analyses in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 29(5):944–950

    Article  CAS  PubMed  Google Scholar 

  30. Dimsdale J, Ziegler M, Ancoli-Israel S, Clausen J (1995) The effect of sleep apnea on plasma and urinary catecholamines. Sleep 18:377–381

    CAS  PubMed  Google Scholar 

  31. Edwards B, Sands S, Skuza E et al (2008) Increased peripheral chemosensitivity via dopaminergic manipulation promotes respiratory instability in lambs. Respir Physiol Neurobiol 164:419–428

    Article  CAS  PubMed  Google Scholar 

  32. Xie A, Wong B, Phillipson E et al (1995) Interaction of hyperventilation and arousal in the pathogenesis of idiopathic central sleep apnea. Am J Respir Crit Care Med 152:1950–1955

    Article  CAS  PubMed  Google Scholar 

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Compliance with ethical guidelines

Conflict of interest. T. Bitter, L. Faber, W. Scholz, H. Fox, C. Prinz, D. Horstkotte, and O. Oldenburg state that there are no conflicts of interest. The accompanying manuscript does not include studies on humans or animals.

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Authors and Affiliations

  1. Klinik für Kardiologie, Herz- und Diabeteszentrum Nordrhein-Westfalen, Universitätsklinikum der Ruhr-Universität Bochum, Bad Oeynhausen, Germany

    T. Bitter, L. Faber, W. Scholz, H. Fox, C. Prinz, D. Horstkotte & O. Oldenburg

  2. Klinik für Pneumologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Germany

    T. Bitter

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  1. T. Bitter
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  2. L. Faber
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  3. W. Scholz
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  4. H. Fox
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  5. C. Prinz
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  6. D. Horstkotte
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  7. O. Oldenburg
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Correspondence to T. Bitter.

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Bitter, T., Faber, L., Scholz, W. et al. Platypnea-orthodeoxia syndrome due to patent foramen ovale. Herz 39, 94–97 (2014). https://doi.org/10.1007/s00059-014-4064-7

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