The Use of Plants and Plant Cell Cultures for the Bioproduction of Proteins
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In the last decade, the technique to genetically modify crop plants has gained more and more interest in terms of bioproduction of heterologous proteins. Plants have been discovered as a possible source for large amounts of cost-effective recombinant protein. Main application field are therapeutics for use in animal and human health, diagnostics and technical enzymes. This review is focussed on the recent progress in this field of molecular farming. After a comparison with hitherto established protein production systems, the advantages of plants as an alternative production system are discussed. An overview about the different host plants and possible expression strategies is given and the progress in commercialization of the techniques is highlighted.
Key words.Bioproduction gene expression molecular farming recombinant protein transgenic plants
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