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Inflammation Research

, Volume 50, Supplement 1, pp 24–29 | Cite as

Meloxicam in acute episodes of soft-tissue rheumatism of the shoulder

  • L. Vidal
  • W. Kneer
  • M. Baturone
  • R. Sigmund
  • 52 Downloads

Abstract:

Objective: This double-blind, randomised trial compared the efficacy and safety of meloxicam vs piroxicam in patients with soft-tissue rheumatism of the shoulder.¶Subjects: 599 outpatients at 88 centres in 9 countries.¶Treatment and Methods: Oral meloxicam 7.5 mg, meloxicam 15 mg or piroxicam 20 mg, once-daily for 14 days. The primary efficacy endpoint was the assessment of pain on day 7 relative to day 1.¶Results: Once-daily treatment with meloxicam 7.5 or 15 mg was comparable to piroxicam. A significantly higher proportion of meloxicam-treated patients had pain relief within day 1 or day 3. The incidence and intensity of adverse events was comparable between the treatment groups, although fewer patients in the meloxicam groups withdrew due to adverse events. There were no apparent differences between the two meloxicam doses.¶Conclusions: Treatment with meloxicam was at least as effective as treatment with piroxicam, with a favourable global tolerability for both doses of meloxicam.¶

Key words: Meloxicam - Rheumatoid arthritis - Non-steroidal anti-inflammatory drugs 

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Copyright information

© Birkhäuser Verlag, 2001

Authors and Affiliations

  • L. Vidal
    • 1
  • W. Kneer
    • 2
  • M. Baturone
    • 3
  • R. Sigmund
    • 4
  1. 1.Boehringer Ingelheim Peru, Av. República de Panamá 2557 - Apartado 3915, Lima 100, Perú, Fax: 51 - 1 470 6231, e-mail: VIDAL@lim.Boehringer-Ingelheim.com PE
  2. 2.Tuttlinger Str.1, 78333, Stockach, GermanyDE
  3. 3.Hospital Vigil de Quiñones, Seville, SpainES
  4. 4.Boehringer Ingelheim, Dept. of Medical Data Services (Biometrics) Biberach an der Riss, GermanyDE

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