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Archives of Orthopaedic and Trauma Surgery

, Volume 120, Issue 1–2, pp 42–47 | Cite as

Chondromyxoid fibroma of bone

  • H. R. Dürr
  • A. Lienemann
  • A. Nerlich
  • B. Stumpenhausen
  • H. J Refior
Original article

Abstract

Chondromyxoid fibroma is a benign, although potentially aggressive tumor, with a cartilage-like matrix, accounting for approximately 1% of all bone tumors. It usually affects the metaphyseal region of long bones of patients in their first or second decade of life. An additional peak of incidence has been observed between 50 and 70 years of age. Three cases are presented here: 10-, 13-, and 52-year-old patients, with lesions in the proximal tibia, the proximal humerus, and the proximal femur, respectively. The literature is reviewed in terms of clinical behavior, diagnostic procedures, prognostic factors, treatment, and outcome. Preferred treatment is complete local excision with tumor-free margins. Intralesional curettage with or without local adjuvants shows a local recurrence rate of approximately 25%. Radiation therapy may be useful in nonresectable cases but bears the well documented risk of radiation-induced malignancies.

Keywords

Local Recurrence Proximal Femur Bone Tumor Prefer Treatment Local Excision 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • H. R. Dürr
    • 1
  • A. Lienemann
    • 2
  • A. Nerlich
    • 3
  • B. Stumpenhausen
    • 1
  • H. J Refior
    • 1
  1. 1.Orthopädische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Klinikum Großhadern, Marchioninistrasse 15, D-81366 Munich e-mail: hrduerr@ort.med.uni-muenchen.de Tel.: +49-89-7095-1, Fax: +49-89-7095–8881DE
  2. 2.Institute of Radiology, Ludwig-Maximilians-Universität, Klinikum Grosshadern, Munich, GermanyDE
  3. 3.Institute of Pathology, Ludwig-Maximilians-Universität, Klinikum Grosshadern, Munich, GermanyDE

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