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Synthesis of thiazoles and thiadiazoles from 1,2-bis(diazoacetyl)ethane

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The reaction of 1,2-bis (diazoacetyl) ethane (diazan) with phenyl isothiocyanate and urea leads to the formation of 1,4-diketo-1,4-bis(5-phenylamino-1,2,3-thiadiazolyl)-butane and 1,2-bis(2-amino-1,3-thiazolyl)ethane, respectively.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 209–211, February, 1980.

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Kartsev, V.G., Medvedev, F.A. & Voronina, G.N. Synthesis of thiazoles and thiadiazoles from 1,2-bis(diazoacetyl)ethane. Chem Heterocycl Compd 16, 151–154 (1980). https://doi.org/10.1007/PL00020723

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  • DOI: https://doi.org/10.1007/PL00020723

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