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Survey of Staphylococcal Enterotoxin Genes, Exfoliative Toxin Genes, and Toxic Shock Syndrome Toxin 1 Gene in Non-Staphylococcus aureus Species

  • K. Becker
  • G. Haverkämper
  • C. von Eiff
  • R. Roth
  • G. Peters
Concise Article
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Abstract

 The aim of this study was to analyze the presence of staphylococcal exotoxin genes in staphylococci other than Staphylococcus aureus. Whereas for Staphylococcus aureus a large spectrum of different exotoxins responsible for toxin-mediated diseases has been described, only few and conflicting data are available regarding toxin production in all other staphylococcal species. A collection of clinical non-Staphylococcus aureus staphylococcal isolates were systematically screened for the presence of genes for toxic shock syndrome toxin 1, exfoliative toxins, and classical enterotoxins by using multiplex polymerase chain reaction enzyme immunoassays. In a total of 461 isolates of 18 different (sub)species derived from clinical specimens, no toxin gene sequences were amplified. The results indicate that the occurrence of toxin genes involved in staphylococcal toxin-mediated diseases is at least very rare in human-derived isolates of non-Staphylococcus aureus species.

Keywords

Multiplex Polymerase Chain Reaction Toxin Production Toxin Gene Toxic Shock Syndrome Staphylococcal Enterotoxin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • K. Becker
    • 1
  • G. Haverkämper
    • 1
  • C. von Eiff
    • 1
  • R. Roth
    • 1
  • G. Peters
    • 1
  1. 1.Institut für Medizinische Mikrobiologie, Universitätsklinikum Münster Domagkstraße 10, 48149 Münster, Germany e-mail: kbecker@uni-muenster.de Tel.: +49-251-8355360 Fax: +49-251-8355350DE

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