Advertisement

Candida tropicalis and Penicillium marneffei Mixed Fungaemia in a Patient with Waldenström's Macroglobulinaemia

  • S. S. Y. Wong
  • P. C. Y. Woo
  • K. Y. Yuen
Note

Abstract

 A patient with Waldenström's macroglobulinaemia who had previously been treated with cladribine presented with septic arthritis caused by Escherichia coli. The patient's condition subsequently deteriorated, and he succumbed to pneumonia and mixed fungaemia due to Candida tropicalis and Penicillium marneffei. Profound lymphopenia coexisted with fungaemia. This is the first reported case of mixed Penicillium marneffei and Candida fungaemia and penicilliosis marneffei in a patient with Waldenström's macroglobulinaemia. Penicilliosis marneffei should be considered as a potential complication in patients with markedly impaired cell-mediated immunity who have travelled to or resided in endemic areas. Patients who have undergone therapy with purine nucleoside analogues such as fludarabine and cladribine are also at risk.

Keywords

Pneumonia Purine Nucleoside Endemic Area Fludarabine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • S. S. Y. Wong
    • 1
  • P. C. Y. Woo
    • 1
  • K. Y. Yuen
    • 1
  1. 1.Division of Infectious Diseases, Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, Republic of China e-mail: kyyuen@hkucc.hku.hk Tel.: +852-28553206 Fax: +852-28551241CN

Personalised recommendations