Bioprocess Engineering

, Volume 17, Issue 3, pp 131–137 | Cite as

Predicting the performance of immobilized enzyme reactors using reversible Michaelis–Menten kinetics

  • I. M. Abu-Reesh


A general mathematical model is developed in the present work for predicting the steady state performance of immobilized enzyme reactor performing reversible Michaelis - Menten kinetics. The model takes into account the effect of external diffusional limitations, the axial dispersion and the equilibrium constant on reactor performance quantified as relative substrate conversion and yield.

The performance of reactor is characterized using the dimensionless parameters of Damkohler number, Stanton number, Peclet number, the equilibrium constant and the dimensionless input substrate concentration.

The reactor performance is described for the two extreme cases of plug flow reactor (PFR) and continuous stirred tank reactor (CSTR) in addition to the intermediate case of dispersed plug flow reactor (DPFR).

The performance of reactor is compared for the two cases of zero order and reversible first order kinetics.


Equilibrium Constant Peclet Number Plug Flow Reactor Performance Plug Flow Reactor 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • I. M. Abu-Reesh
    • 1
  1. 1.Chemical Engineering Department, The University of Jordan, Amman 11942, JordanJO

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