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Morphological Considerations of Peri- and Myocarditis

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Abstract

In medicine, and thus in pathology, there are areas/topics of fashion and they shift from time to time. Pericardial diseases are not fashionable. Myocarditis is, and has been for a long time. Due to new ways of retrieving tissue samples from the pericardium the modern diagnostic tools such as immunohistochemistry and molecular pathology can be applied in this context as they have been in myocarditis for a long period. The diagnosis of inflammation rests on many other findings than morphological alterations and it is indeed questionable if inflammation is solely a morphological diagnosis. The methodologies of pathology can be improved and used in a better and more purposeful way even under routine conditions. It is concluded that morphology is still mandatory to make a final diagnosis of peri- and myocarditis.

Zusammenfassung

Obwohl Perikarderkrankungen lange Zeit nicht im Vordergrund des Interesses der Pathologen standen, ermöglichen neue Techniken zur Entnahme von Perikardgewebe die Anwendung neuer diagnostischer Methoden der Immunhistochemie und Molekularpathologie, die sich in der Myokarditisdiagnostik bereits bewährt haben. In diesem Zusammenhang stellt sich die Frage, ob die Diagnose einer Entzündung nur auf der Grundlage von morphologischen Veränderungen gestellt werden kann. Eine endgültige Diagnose einer Perikarditis oder Myokarditis erscheint aber ohne morphologische Kriterien kaum möglich.

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Baandrup, U. Morphological Considerations of Peri- and Myocarditis. Herz 25, 724–728 (2000). https://doi.org/10.1007/PL00001989

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  • DOI: https://doi.org/10.1007/PL00001989

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